Moesin (human) (rec.)
|Synonyms||MSN; Moesin; Membrane-organizing Extension Spike Protein|
Activity has not been tested.
|Formulation||Lyophilized from 20mM HEPES, pH7.0.|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Declaration||Manufactured by AbFrontier|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Handling Advice||Avoid freeze/thaw cycles.|
|Use/Stability||After reconstitution, store at -80°C.|
|Product Specification Sheet|
Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. The ERM proteins have a crucial role in organizing membrane domains through their ability to interact with transmembrane proteins and the cytoskeleton. The C-terminal domain may form an intramolecular band to the N-terminal four-point-one ERM homology domain or may bind to F-actin depending on the phosphorylation state of a conserved threonine residue (Thr567 in ezrin, Thr564 in radixin, and Thr558 in moesin). An essential role of the 78-kDa protein Moesin is described for Rho- and Rac-dependent assembly of actin filaments.
1) Rudiger Blindta et al., (2002) Cardiovascular Research 54:630–639. (General)
2) Xiaohua Guo et al.,Am J Physiol Heart Circ Physiol|(2009) 297: H238–H246. (General)