Moesin (human) (rec.)

CHF 366.00
In stock
YIF-LF-P03870.2 mgCHF 366.00
More Information
Product Details
Synonyms MSN; Moesin; Membrane-organizing Extension Spike Protein
Product Type Protein
Properties
Source/Host E. coli
Crossreactivity Human
Purity ≥95% (SDS-PAGE)
Formulation Lyophilized from 20mM HEPES, pH7.0.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability After reconstitution, store at -80°C.
Documents
MSDS No
Product Specification Sheet
Datasheet Download PDF

Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. The ERM proteins have a crucial role in organizing membrane domains through their ability to interact with transmembrane proteins and the cytoskeleton. The C-terminal domain may form an intramolecular band to the N-terminal four-point-one ERM homology domain or may bind to F-actin depending on the phosphorylation state of a conserved threonine residue (Thr567 in ezrin, Thr564 in radixin, and Thr558 in moesin). An essential role of the 78-kDa protein Moesin is described for Rho- and Rac-dependent assembly of actin filaments.

Product References

1) Rudiger Blindta et al., (2002) Cardiovascular Research 54:630–639. (General)
2) Xiaohua Guo et al.,Am J Physiol Heart Circ Physiol|(2009) 297: H238–H246. (General)

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