anti-Ferredoxin Reductase, pAb

CHF 315.00
In stock
YIF-LF-PA0003100 µlCHF 315.00
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Product Details
Synonyms AR; ADXR; FDXR; EC=; Ferredoxin Reductase; Adrenodoxin Reductase; Ferredoxin-NADP(+) Reductase; NADPH:Adrenodoxin Oxidoreductase, Mitochondrial
Product Type Polyclonal Antibody
Immunogen/Antigen Recombinant human fragment protein purified from E. coli.

Western Blot (1:3,000)
Immunoprecipitation (1 μl)

Crossreactivity Human
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Isotype Negative Control

Rabbit IgG

Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

Ferredoxin reductase is a ubiquitous flavoenzyme, containing noncovalently bound FAD as a prosthetic group (1). It plays a role in delivering NADPH or low potential one-electron donors such as ferredoxin and flavodoxin to redox-based metabolisms in plastids, mitochondria and bacteria (2). In mammals, ferredoxin reductase is loosely associated with the inner mitochondrial membrane and receives electrons from NADPH. These electrons are transferred to ferredoxin which shuttles electrons to cytochrome P450 in the adrenal cortex mitochondrial steroid hydroxylation systems (3). Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-β hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

Product References

1) Carrillo, N. and Ceccarelli, E. D. (2003) Eur. J. Biochem. 270, 1900-1915. (General)
2) Lambeth, J. D. and Kamin, H. (1977) J.Biol. Chem. 252, 2908-2917. (General)
3) Lin, D. et al. (1990) Proc. Natl. Acad. Sci. USA. 87, 8516-8520. (General)

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