anti-Methionine Sulfoxide Reductase B, pAb

CHF 322.00
In stock
YIF-LF-PA0088100 µlCHF 322.00
 
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Product Details
Synonyms SelR; SelX; Sepr; Msrb1; MsrB1; EC=1.8.4.-; Selenoprotein R; Selenoprotein X; Methionine-R-Sulfoxide Reductase B1
Product Type Polyclonal Antibody
Properties
Immunogen/Antigen Recombinant mouse MSRB protein purified from E. coli.
Application Western Blot (1:1,000~2,000)
Crossreactivity Human
Mouse
Rat
Purity Detail Protein A purified.
Concentration 1 mg/ml
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS No
Product Specification Sheet
Datasheet Download PDF
Methionine sulfoxide reductase B (MsrB), also known as SelX, is a selenoprotein. The oxidation of methionine at the sulfur atom leads to alternative epimers: R form of Met(O) and S form of Met(O). MsrB can reduce R form of both free and protein-incorporated methionine sulfoxide to methionine. It has a crucial role in protecting cells against oxidative damages. MsrA reduces only the S epimer of Met(O), and MsrB reduces the R epimer of Met(O) in proteins. Although the catalytic mechanisms of MsrA and MsrB are similar, two Msrs have no sequence identity and no structural similarity.
Product References
1) Zheung D. et al., (2003) J Biomol NMR. 27:183-184. (General)
2) Weissbach H., (2002) Arch Biochem Biophys. 397:172-178. (General)
3) Kryukov, G., (2002) Proc Natl Acad Sci USA. 99:4245-4250. (General)
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