anti-Transthyretin, pAb

CHF 315.00
In stock
YIF-LF-PA0102100 µlCHF 315.00
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Product Details
Synonyms TTR; TBPA; ATTR; PALB; Prealbumin; Transthyretin
Product Type Polyclonal Antibody
Immunogen/Antigen Recombinant human protein purified from E. coli.

Western Blot (1:2,000)
Immunoprecipitation (1 μl)

Crossreactivity Human
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition. Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Product References

1) Hamilton, J.A. and Benson, M.D. (2001) Cell. Mol. Life Sci. 58, 1491-1521. (General)
2) Shirahama, T. et al. (1982) Am. J. Path. 107, 41-50. (General)
3) Episkopou, V. et al. (1993) Proc. Nat. Acad. Sci. 90, 2375-2379. (General)
4) Saraiva, M.J.M. (1995) Hum. Mutat. 5, 191-196. (General)
5) Pfeffer, B. et al. (2004) Mol. Vis. 10, 23-30. (General)

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