anti-α-Tubulin, pAb
| Product Details | |
|---|---|
| Synonyms | TUBA3; TUBA1A; α-Tubulin 3; Tubulin B-α-1; Tubulin α-3 Chain; Tubulin α-1A Chain |
| Product Type | Polyclonal Antibody |
| Properties | |
| Immunogen/Antigen | Synthetic peptide (KLH coupled) corresponding to C-terminal residues of human tubulin. |
| Application |
Western Blot (1:10,000) |
| Crossreactivity |
Human Mouse Rat |
| Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Tubulin is a heterodimer consisting of α and β-tubulin subunits. It is nearly ubiquitous among eukaryotic cells. The α and β tubulins, which are each about 55 kDa MW, are homologous but not identical. α-β tubulin heterodimer is the basic building block of microtubules. This intracellular cylindrical filamentous structure is present in almost eukaryotic cells. microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α-chain.
1) Blose SH, et. al. Journal of Cell Biology (1984), 98(3):847-58. (General)
2) Breitling F, et. al. Journal of Molecular Biology (1986) 189(2):367-70. (General)
3) Biochim Biophys Acta (1989), 1012(1):46-56. (General)
4) Biochemistry (1993) 32(18):4955-61. (General)
