anti-γ-Synuclein, pAb

CHF 322.00
In stock
YIF-LF-PA0196100 µlCHF 322.00
 
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Product Details
Synonyms SR; SNCG; BCSG1; Persyn; Synoretin; γ-Synuclein; Breast Cancer-specific Gene 1 Protein
Product Type Polyclonal Antibody
Properties
Immunogen/Antigen Recombinant human His-γ Synuclein protein purified from E. coli.
Application Western Blot (1:2,000)
Crossreactivity Human
Purity Detail Affinity purification.
Formulation Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Declaration Manufactured by AbFrontier
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS No
Product Specification Sheet
Datasheet Download PDF
Synuclein is a small, soluble protein primarily expressed in neural tissue. The synuclein family includes three known proteins: α-synuclein, β-synuclein, and γ-synuclein. γ-Synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. γ-Synuclein expression in breast tumors is a marker for tumor progression. Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
Product References
1) Irvine GB et al., (2008) Mol Med. (General)
2) Wakabayashi K et al., (2007) Neuropathology 27(5):494-506. (General)
3) Beyer K., Acta Neuropathol 112(3):237-251. (General)
4) Bruening W et al., (2000) Cancer 88(9):2154-2163. (General)
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