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anti-γ-Synuclein, pAb
Product Details | |
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Synonyms | SR; SNCG; BCSG1; Persyn; Synoretin; γ-Synuclein; Breast Cancer-specific Gene 1 Protein |
Product Type | Polyclonal Antibody |
Properties | |
Immunogen/Antigen | Recombinant human His-γ Synuclein protein purified from E. coli. |
Application |
Western Blot (1:2,000) |
Crossreactivity | Human |
Purity Detail | Affinity purification. |
Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
Declaration | Manufactured by AbFrontier |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet |
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Synuclein is a small, soluble protein primarily expressed in neural tissue. The synuclein family includes three known proteins: α-synuclein, β-synuclein, and γ-synuclein. γ-Synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. γ-Synuclein expression in breast tumors is a marker for tumor progression. Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
1) Irvine GB et al., (2008) Mol Med. (General)
2) Wakabayashi K et al., (2007) Neuropathology 27(5):494-506. (General)
3) Beyer K., Acta Neuropathol 112(3):237-251. (General)
4) Bruening W et al., (2000) Cancer 88(9):2154-2163. (General)