anti-β-Actin (N-term), pAb
| Product Details | |
|---|---|
| Synonyms | ACTB; Loading Control |
| Product Type | Polyclonal Antibody |
| Properties | |
| Immunogen/Antigen | Synthetic peptide (KLH coupled) corresponding to N-terminal residues of human β actin. |
| Application |
Western Blot (1:10,000) |
| Crossreactivity |
Human Mouse Rat |
| Purity Detail | Protein A purified. |
| Concentration | 1 mg/ml |
| Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Actin is an abundant cytoskeletal protein found in all mammalian cells. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner. α and β-cytoplasmic actins are expressed in a wide variety of cells. Whereas, expression of α-skeletal, α-cardiac, α-vascular and γ-enteric actins are more restricted to specialized muscle cell type. Actin's filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
1) True, L.D. Atlas of Diagositc Immunopathology. (1990) Gower Medical Publishing. N.Y.6.5. (General)
2) Otey C et al. J.Cell Biol. (1986) vol.102: pp.1726-1737. (General)
3) Reddy S et al. J.Biol. Chem. (1990) vol.262: pp.1863-1867. (General)
