anti-β-Actin (N-term), pAb

Actin is an abundant cytoskeletal protein found in all mammalian cells. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner. α and β-cytoplasmic actins are expressed in a wide variety of cells. Whereas, expression of α-skeletal, α-cardiac, α-vascular and γ-enteric actins are more restricted to specialized muscle cell type. Actin's filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.