anti-CSPS (Catecholamine-sulfating Phenol Sulfotransferase), pAb
| Product Details | |
|---|---|
| Synonyms | STM; M-PST; HAST3; TL-PST; SULT1A3; EC=2.8.2.1; ST1A3/ST1A4; Sulfotransferase 1A3/1A4; Aryl Sulfotransferase 1A3/1A4; Placental Estrogen Sulfotransferase; Thermolabile Phenol Sulfotransferase |
| Product Type | Polyclonal Antibody |
| Properties | |
| Immunogen/Antigen | Recombinant human protein purified from E. coli. |
| Application |
Western Blot (1:500~2,000) |
| Crossreactivity | Human |
| Purity Detail | Protein A purified. |
| Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
The human Catecholamine-Sulfating Phenol Sulfotransferase (CSPS) is the only sulfotransferase that catalyses the sulfation of catecholamins, in particular the neurotransmitter dopamine, with high activity. CSPS is required for stimulation by Mn2+ of the sulfating activity and expressed in the human intestine, brain, platelet and other tissues. In the brain it may play a role in regulating the levels of dopamine. It also serves as a detoxifying function in the intestine, where it may detoxify potentially lethal dietary monoamines. Catalyzes the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.
1) Pai, T.G. et al. (2003) J. Biol. Chem. 278, 1525-1532. (General)
2) Pai, T.G. et al. (2002) J. Biol. Chem. 277,43813-43820. (General)
3) Coughtrie, M.W.H. (2002) Pharmacogenomics J. 2, 297-308. (General)
