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anti-TNFα, pAb
Product Details | |
---|---|
Synonyms | Cachectin |
Product Type | Polyclonal Antibody |
Properties | |
Source/Host | Rabbit |
Immunogen/Antigen | Recombinant mouse protein. |
Application |
Western Blot |
Crossreactivity | Mouse |
Purity Detail | Affinity purification. |
Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
Declaration | Manufactured by AbFrontier |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet |
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Tumor Necrosis Factor (TNF-α) is a cytokine which is involved in the inflammatory process. It is produced chiefly by activated macrophages (M1), although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells and neurons. TNF-α is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism and coagulation. TNF-α is a trimeric protein encoded within the major histocompatibility complex. It was first identified in its 17 kd secreted form, but further research then showed that a noncleaved 27kd precursor form also existed in transmembrane form.