Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
AdipoGen Life Sciences
anti-Obestatin (human), pAb
190
CHF
CHF 190.00
In stock
AG-25A-0043-C100100 µgCHF 190.00
Figure 1: ELISA (indirect: 1:20’000.): Analysis of production of anti-Obestatin (human), pAb (Prod. No. AG-25A-0043) after peptide immunization.
| Product Details | |
|---|---|
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | Synthetic peptide corresponding to aa 76-98 (F76NAPFDVGIKLSGVQYQQHSQAL98) of human obestatin. |
| Application |
ELISA: (direct and indirect: 1:2’000-1:5’000) Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS. |
| Crossreactivity |
Human Mouse |
| Specificity |
Recognizes human obestatin. Cross-reacts with mouse obestatin. |
| Purity Detail | Protein A-affinity purified. |
| Concentration | 1mg/ml |
| Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. |
| Isotype Negative Control | |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Obestatin derives like ghrelin from proghrelin, but exhibits opposite physiological effects. Obestatin decreases food intake and body weight in rodents. Moreover, obestatin also counteracts ghrelin’s effect by decelerating gastric emptying and decreasing intestinal contractility. Obestatin binds to orphan G protein-coupled receptor GPR39. Amidation of the C-terminus seems to be important for obestatin’s activity.