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Innovative Research Reagents for Inflammation & Immune Responses

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Vector LabsCayman ChemicalB Cell Expansion ToolNLRP3 Inflammasome Starter SetsManumycin A - Exosome Biogenesis InhibitorAPO-1 Apoptosis Inducing AntibodiesProgranulinRevMab BiosciencesBellbrook Labs cGamp cGas AssayImmuno-Oncology Biomarker ELISA AssaysAPRIL and BAFFFunctional Antibodies 2019

New Products Archive

Latest Product Highlights Archive

VSTM5 - A Novel Immune Checkpoint regulating Treg Generation
VSTM5 (human):Fc (human) (rec.) (non-lytic)

FNDC4 a New Marker for Inflammatory Metabolic Disease
NEW - FNDC4 (human) ELISA Kit

Create a BAFF KO phenotype in Mice by One Injection
anti-BAFF (mouse), mAb (blocking) (Sandy-2) (preservative free)

Potent Regulator of Epithelial Homeostasis - In Vivo
IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)

Sensitive & Specific Analysis of PGRN/GRN Mutations
NEW - Progranulin (human) ELISA Kit (mAb/mAb)

Potent Exosome Secretion Inhibitor
Manumycin A - BULK Available!

Active Inhibitory Receptor Immune Checkpoint
CD152 [CTLA-4] (human) (rec.) (His)

New Potential Biomarker of Glioblastoma
FNDC4 (human) ELISA Kit

A new Exerkine that Suppresses Food Intake and Obesity
Lac-Phe . acetate [N-Lactoyl-L-phenylalanine]

Unique Progranulin Protein Strongly Binding to Sortilin
Progranulin (human) (rec.) (untagged)

New Neuroprotective Agent Reducing Intracellular Oxidative Stress
Collinolactone

New KO Validated NLRP1b Inflammasome Antibody
anti-NLRP1b (mouse), mAb (2A12)

Flagellin - Potent TLR5 and/or NLRC4 Agonist
High Purity - Recombinant - NLRC4 & TLR5 Mutants

IL-2 Monomeric Proteins with Enhanced Activity & Stability
IL-2 Superkine H9T (monomeric):Fc-KIH (human) (rec.)

Sensitive Detection of a Novel Player in Metabolic Diseases
NEW Asprosin (human) ELISA Kit

A New Hunger Factor Involved in Obesity
Acyl-CoA-binding Protein (human) ELISA Kit

Improved Engineered Standard 9E10 Animal-free anti-c-Myc Tag Antibody
anti-c-Myc, mAb (rec.) (9E10 improved variant)

Animal-free Recombinant Secondary Antibodies for Reproducible Results
anti-IgG (human), mAb (rec.) Multiclonal

Validated Antibodies for Inflammatory Cell Death Research
PANoptosome Antibodies Starter Sets

New Potent Monoclonal Antibody for Mouse APRIL Depletion
anti-APRIL (mouse), mAb (blocking) (Centotto-1) (preservative free)

New & Unique SARS-CoV-2 Delta Variant Assay!
SARS-CoV-2 Neutralizing Antibodies Detection Kit (Delta Variant)

Tool to differentiate THP-1 Cells into M0 Macrophages
Phorbol 12-myristate 13-acetate [PMA] - BULK Available

Measure Inflammasome Activation In Vivo using Asc Speck Formation
anti-Asc, pAb (AL177) (preservative free)

Potent Activator of NLRP1 Inflammasome via DPP9 Inhibition
Talabostat . mesylate

Potent SARS-CoV-2 Frameshift Inhibitor
Merafloxacin

Recombinant Fc-FNDC4 for In Vivo Studies - BULK Available!
Fc (human):FNDC4 (rec.)

New SARS-CoV-2 Variants for Antibody Screening Applications
SARS-CoV-2 S1 (RBD):Fc Delta & Delta Plus Variants

Potent & Selective NLRP3 Inflammasome Inhibitor for In Vivo Studies
Dapansutrile

Novel Chaperone-mediated Autophagy Activator
CA77.1

SARS-CoV-2 Variants Neutralizing Antibodies Detection Kits
Unique Assays for Variants B.1.1.7, P.1 and B.1.351

NINJ1 - Essential Protein for Pyroptosis Research
anti-NINJ1, pAb (IN114)

Potential New SARS-CoV-2 MPro Inhibitor
Euphol

Unique Human Gasdermin E (C-terminus) Detection Assay
Gasdermin E (human) ELISA Kit

Stabilizers of Biological Structures & Macromolecules
Ectoine, Hydroxyectoine, Glucosylglycerol & Ready-to-use Buffers

Unique Neutralizing Reagent to Study Human & Mouse IL-33
HpARI (Alarmin Release Inhibitor) (rec.) (His)

GBP1, a Key Factor in Gasdermin D-dependent Pyroptosis
anti-GBP1 (human), pAb (IN111)

Active & Stable Trimeric SARS-CoV-2 Protein
SARS-CoV-2 Spike Protein (D614G) (Stable Trimer) (rec.) (His)

New Biomarker for Obesity Research
Acyl-CoA-binding Protein (human) ELISA Kit

Potent & Selective MEK1 and MEK2 Inhibitor
PD 0325901 [Mirdametinib]

High Specificity SARS-CoV-2 Neutralizing Antibodies Assay
SARS-CoV-2 Neutralizing Antibodies Detection Kit

NEW Sensitive & Specific Colorimetric Sandwich Assay
ACE2 (human) ELISA Kit

Potent Multi-targeted Receptor Tyrosine Kinase Inhibitor
Pazopanib - BULK Available!

Potent & Selective Lysine Methyltransferase EZH2 Inhibitor
EPZ-6438 [Tazemetostat] - BULK Available

Potent Inhibitor of ARDS in COVID-19 - BULK Available
VIP (human, mouse, rat) . AcOH [RLF-100; Aviptadil]

Specific Detection of Unphosphorylated Human FADD
anti-FADD (human), mAb (1C4)

Very Specific Detection of Human Anti-SARS-CoV-2 IgG
SARS-CoV-2 (Spike RBD) IgG Serological ELISA Kit

Faster and Easier Measurement of SARS-CoV-2 Neutralizing Antibodies
SARS-CoV-2 Neutralizing Antibodies Detection Kit

HTS Detection Assay to Determine SARS-CoV-2 Blocking Agents
New SARS-CoV-2 Inhibitor Screening Kit

Potent TRPV1 Agonist - Available From Stock
Resiniferatoxin

Major Immune Inhibitory Ligand of LAG-3 - NEW Biomarker
FGL1 (human) ELISA Kit

Small Molecule Inhibitors for SARS-CoV-2 Research
Remdesivir, Lopinavir, Darunavir, Oseltamivir, Camostat mesylate ... and more

New ACE2 Blocking Antibody
anti-ACE2 (human), mAb (blocking) (AC384) (preservative free)

Detects the SARS-CoV-2 Receptor by FACS
anti-ACE2 (human), mAb (AC18F)

Broad Panel of LAG-3 Immuno-Oncology Reagents
Potent Functional Antibodies & Recombinant Proteins

Major Immune Inhibitory Ligand of LAG-3 - NEW Biomarker
FGL1 (human) Matched Pair Detection Set

The Standard Cell-permeable Zn2+-selective Indicator
Zin3 AM

Newly Available: APO-1-1 for IHC Applications
anti-Fas (human), mAb (APO-1-1) (preservative free)

New Antibiotic against MRSA, MSSA and VISA
PK150 (Sorafenib Analog)

NEW Potent Mitochondrial ATP Synthase Inhibitor
S-Gboxin iodide

Potent 20S Proteasome Inhibitor - Lower Prices!
Salinosporamide A

NEW Caloric Restriction Mimetic & Autophagy Inducer
3,4-Dimethoxychalcone

VISTA is an Acidic pH-selective Ligand for PSGL-1
PSGL-1 (human):Fc (human) (rec.)

New Sensitive Assays to Detect Stimulation of Erythropoiesis
Erythroferrone (human) Detection Set & ELISA Kit

TRBC1-specific Antibody for T Cell Immunophenotyping
anti-TCR Cβ1 (human), mAb (Jovi-1)

Create a BAFF KO phenotype in Mice by One Injection
anti-BAFF (mouse), mAb (blocking) (Sandy-2) (preservative free)

OXPHOS Inhibitor & Anticancer Agent - BULK!
Rottlerin

NEW Parkin Tools for Parkinson Research
Parkin E3 Ligase TR-FRET Kit & Protein

Best Test for Specific Activity of 20S Proteasome
20S Constitutive Proteasome Assay Kit

Oxidative Phosphorylation Inhibitor
Averufin

Potent FLT3 Tyrosine Kinase Inhibitor
Sunitinib Malate - BULK Available!

New Human APRIL Blocking Antibody
anti-APRIL (human), mAb (blocking) (Mahya-1)

Biomarker for Hepatocellular Carcinoma Prognosis
Highly Sensitive IL-36α (human) ELISA Kit

Potent Neutrophil Elastase Inhibitor - BULK Available
GW311616A [Lower Prices]

Broad Range of New High Quality Polyubiquitin Chains
Linkage-specific Ubiquitin Chains from SouthBayBio

New Highly Reproducible & Sensitive Human ICOSL Assay
ICOSL (B7-H2/CD275) (human) ELISA Kit

Newly Available Immune Checkpoint Assay
CD40L (human) ELISA Kit

Diagnosing DLK1-related Disorders during Pregnancy
DLK1, Soluble (human) ELISA Kit - From Stock

Potent Deoxyhypusine Synthase (DHPS) Inhibitor
GC7 - Tool for Immunometabolism Research

Potent FTO Inhibitor - Modulating Thermogenesis
Entacapone

Unique TGFβ1 with Long Half-life for In Vivo Studies
TGFβ1 (mutant) (human):Fc (human) (rec.)

New LAG-3 Ligand for Immuno-Oncology Research
Fibrinogen-like Protein 1 [FGL1]

Potent Inflammasome Inhibitor for In Vivo Studies
MCC950 . sodium salt - BULK available

New Selective 'PARP-14 M2' Inhibitor
GeA-69

Iron Metabolism & Cardiovascular Protection Biomarker
Erythroferrone (human) ELISA Kit

Potent Pentamerized Immune Checkpoint Protein
VISTA (human):COMP (mouse) (rec.) (His)

VISTA:COMP - Immunosuppressive In Vivo Agonist
VISTA (mouse):COMP (mouse) (rec.) (His)

NEW Tool for Energy Metabolism Research
Narciclasine

Potent Tumor Promoter - BULK Available
Phorbol 12-myristate 13-acetate [PMA; TPA]

Potent Monocarbonyl Analog of Curcumin (MAC)
UBS109

Tumor Biomarker for Poor Survival Prognosis
NEW Highly Sensitive PD-L1 (human) ELISA Kit

Biomarker for Immuno-Oncology & Autoimmune Diseases
NEW Highly Sensitive PD-1 (human) ELISA Kit

New Potent Stimulator of iNKT Cells
4-Fluorophenylundecanoyl-α-galactosylceramide

Potent B Cell Expansion - BULK Sizes!
anti-CD40 (mouse), mAb (FGK45)

Selective Protein Degradation Technology Tool (Trim-Away)
Lipoyl-TRIM21 (human) (rec.) (His)

Selective FABP4 Inhibitor & Glucose Uptake Stimulator
BMS-309403

Potent PDE10A Inhibitor & Brown Fat Inducer
PF-2545920

Active Fc-Protein for Tissue Repair Studies - BULK!
IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)

Potent Immune Checkpoint Protein for In Vivo Studies - BULK!
CD152 [CTLA-4] (mouse):Fc (mouse) (rec.) (non-lytic)

Potent MALT1 Inhibitor - BULK Available!
Z-VRPR-FMK

NEW GSDMD-N-induced Pyroptosis Inhibitors
U-73122 & Necrosulfonamide

Flagellin - Potent TLR5 and/or NLRC4 Agonist
High Purity - Recombinant - NLRC4 & TLR5 Mutants

The Standard Kit for a Neurodegenerative Diseases Marker
Progranulin (human) ELISA Kit

First Nucleoside-Analog Potent Bacterial RNAP Inhibitor
Pseudouridimycin [PUM]

NEW Brain Glycogen Phosphorylase (bGP) Agonist
Arzanol

NEW - Sensitive Human Autoimmune Diseases Assay
APRIL (human) ELISA Kit

NEW - Immunoblotting of Gasdermin D (C-terminus)
anti-Gasdermin D (mouse), pAb (IN110)

A NEW Tool to Measure Pyroptosis
Gasdermin D (mouse) ELISA Kit

NEW Potent Anti-inflammatory Agent
Itaconic acid 4-octyl ester [4-Octyl itaconate]

Potent Actin Polymerization Inducer - BULK Available
Jasplakinolide (high purity)

Long-acting Acylated GLP-1 Receptor Agonist
Liraglutide

New Signaling Pathway in Obesity & Insulin Resistance
GFRAL & GDF15 Fusion Proteins

Unique Active Immune Checkpoint Protein
BTNL2 (human):Fc (human) (rec.)

Potent Actin Polymerization Inhibitor
Latrunculin A & B - BULK available

Potent Tetracycline Antibiotic
Viridicatumtoxin

New Tool for Extracellular Vesicle Isolation
Tim-4 (mouse):Fc (human) (rec.) (Biotin)

Potent Immunosuppressant & Anticancer Agent
Everolimus

New Necroptosis Inhibitor
Sibiriline

New & Potent Cancer Metastasis Inhibitor
KBU2046

New Active Immune Checkpoint Protein
BTNL2 (mouse):Fc (mouse) (rec.)

Potent CaMKII Inhibitor - BULK Available
KN-93 (water soluble)

Potent In Vivo B Cell Activator - Reduced Prices!
anti-CD40 (mouse), mAb (FGK45)

Inhibitors of Bacterial DNA-dependent RNAP
Broadest Panel of Rifamycin Derivatives!

The Standard NLRP3 Antibody - Reduced Price!
anti-NLRP3/NALP3, mAb (Cryo-2)

Potent Immunosuppressant & Anticancer Agent
Everolimus

Potent HDAC Inhibitor
Apicidin

Excellent Antibody to Detect Cleaved Mouse IL-1alpha
anti-IL-1alpha (p18) (mouse), mAb (Teo-1)

Economic Production of Nicotinamide Riboside
NAD Nucleotidase (H. influenzae) (rec.)

STANDARD Diabetes Inducer - BULK Available!
Streptozotocin

AMPK Activator Associated With Longevity
MOTS-c (K14Q Mutant) (human)

Unique Antibacterial Class I Lantibiotic
NAI-107 [Microbisporicin]

Active Immunosuppressive Human Arginase I
Arginase I (human) (rec.) (highly active)

New and Potent GLP-1 Receptor Agonist
Semaglutide acetate

Potent Microtubule Inhibitor - BULK
Nocodazole

Diabetes and Obesity Regulator
Neuromedin U-25 (human)

YOU Requested - NOW Available
Asc Antibody (AL177) Blocking Peptide

Convenient Asc (AL-177) Package
Asc (AL177) Antibody + Blocking Peptide Set

NEW Mouse-specific PD-1 Blocking Antibody
anti-PD-1 (mouse), mAb (blocking) (1H10)

Autophagy, Apoptosis and Necroptosis Inducer
Rasfonin

Selective TRPA1 Activator & Headache/Migraine Inducer
Umbellulone

Rare Antitumor Antibiotic - Available from the Source!
Decoyinine

Unique Conformation-specific Tubulin Antibody
anti-Tubulin-GTP, mAb (rec.) (MB11)

Regulation of Allergen-induced Epithelial IL-33 Production
Fc (human):Dectin-1 (mouse) (rec.)

New Biomarker to Measure Maternal Metabolic Adaptations during Pregnancy
DLK1, Soluble (human) ELISA Kit

Potent, Selective & Irreversible 20S Proteasome Inhibitor - BULK
Epoxomicin

Powerful Effector of TetR & revTetR Systems
Anhydrotetracycline . HCl

Unique Tubulin-Modification Specific Antibody
anti-Tubulin (glycylated), pAb (Gly-pep1)

Detection of a New Fasting-induced Protein
Asprosin (human) Matched Pair Detection Set

HRP Substrate for Tyramide Signal Amplification
Biotinyl tyramide

Potent Mitochondria-dependent Apoptosis Inducer
Mensacarcin

New IL-33 Inhibitor
HpARI (Alarmin Release Inhibitor) (rec.) (His)

Highly Active Notch Ligand - BULK Available
DLL1 (mouse):Fc (human) (rec.)

Potent & Selective 20S Proteasome Inhibitor - BULK Available
Epoxomicin

Potent PPAR δ Agonist
GW501516

Specific Vacuolar-type H-ATPase Inhibitor
Bafilomycins

Multimeric APRIL - B Cell Proliferation Stimulator
APRIL (human) (multimeric) (rec.)

Multimeric CD40L - Potent B Cell Activator
CD40L (human) (multimeric) (rec.)

Potent sGC Activator - BULK Available
YC-1

Potent Cell Permeable HDAC Inhibitor
PTACH [NCH 51]

High Sensitive Asthma Biomarker Detection Kit
Periostin (human) ELISA Kit

Active Notch Ligand - BULK Available
Jagged-1 (mouse):Fc (human) (rec.)

GPVI Receptor Agonist for Platelet Receptor Studies
Convulxin

Rapid Apoptosis Inducer with Anticancer Activity
Raptinal

Asprosin - A New Fasting-induced Protein
NEW Asprosin-specific Abs

Unique UBL Protein-Based Substrates
Rhodamine-labeled ISG15 - NEDD8 - SUMO1/2

MegaFasL - Potent Apoptosis Inducer
FasL (human) (multimeric) (rec.)

Potent & Specific H+-ATPase Inhibitors
High Purity Concanamycin A, B & C

Highly Selective Inhibitor for DYKR1A
FINDY

SMN Complex Purification Antibody
anti-Survival Motor Neuron Protein (human), mAb (7B10)

UNIQUE Glycylated Tubulin Antibody
anti-Tubulin (glycylated), pAb (Gly-pep1)

NEW Selective PPARα agonist
Eupatilin

Potent and Selective 20S Proteasome Inhibitor
Epoxomicin

Detecting the AIM2 Inflammasome
anti-AIM2 (human), mAb (3B10)

Enhanced Cytotoxic T Cell Induction
IL-2 Superkine (Fc)

Selective Inhibitor of DYRK1A, DYRK2 & DYRK3
Harmine

Potent Antiproliferative Multi-kinase Inhibitor
Jak/Src Inhibitor 1 [Debio 0617B] . hydrochloride

Potent Notch Ligand with Enhanced Activity 
DLL4 (human):Fc (human) (rec.) (highly active mutant)

Tumor-specific Pyruvate Kinase M2 Inhibitor 
Shikonin

NEW Potent Netrin-1 Blocking Antibody 
anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (preservative-free)

UNIQUE - Detects Monomeric & Dimeric IL-37 
IL-37 (human) ELISA Kit

Potent & Irreversible 20S Proteasome Inhibitor
Salinosporamide A

DYRK1 Inhibitors 
AnnH31 / AnnH75

New Postsynaptic Activity & Plasticity Marker
anti-PSD-95 (palmitoylated), mAb (rec.) (PF11)

High Activity OX40L Multimer Construct
Fc (human):OX40L, Soluble (human) (rec.)

Biologically Active TIM-3 Ligand 
Galectin-9 (human):Fc (human) (rec.)

Potent Mitochondrial Complex II Inhibitor 
Atpenin A5

NEW Potent CD137L Fusion Protein 
Fc (human):CD137L, Soluble (human) (rec.)

Rare Antitumor Antibiotic - Available from Stock! 
Decoyinine

NEW Fasting-induced Protein Hormone 
Asprosin (human) (rec.) (His)

Unique Antibody to Deplete B Cells In Vivo 
anti-BAFF (mouse), mAb (blocking) (Sandy-2)

Potent & Selective Gαq Family Inhibitor 
YM-254890

Alzheimer Inducing Agent 
Fipronil

IL-36γ - Proinflammatory Cytokine 
anti-IL-36γ (human), mAb (Jussy-1)

NEW Factor in Inflammatory Bowel Disease 
FNDC4

Inhibitor of CDK5/p25 and GSK-3β 
Hymenidin

CK2 Inhibitor & Thermogenesis Inducer 
CX-4945 . hydrochloride

Specific Biomarker for Psoriasis 
IL-36γ (human) ELISA Kit

NEW Immune Checkpoint Receptor 
CD112R (mouse):Fc (human) (rec.)

Potent pan-Akt (1/2/3) Inhibitor 
GSK690693

NEW Anticancer Compound 
Jak/Src Inhibitor 1 . hydrochloride

Potential Virulence Factor 
(-)-Mitorubrinic acid

Potent Inhibitor of mPGES-1
Arzanol

NEW Cinnamtannin B-1, Higher Purity >96% HPLC 
Cinnamtannin B-1

Potent Water Soluble JAK1 & JAK2 Inhibitor 
Ruxolitinib . phosphate salt

Biomarker for Airway Inflammation 
anti-Periostin, mAb (Stiny-1)

Lead Compound for DYRK1A Inhibitor Development 
Paprotrain

Significant Marker for Malignancy 
Fibronectin (EDA), mAb (blocking) (IST-9) (preserv. free)

Newly Released Protein – BULK Available 
IL-38 (aa 20-152) (human) (rec.) (His)

Potent & Selective 11β-HSD1 Inhibitor 
Emodin

Cell Death Inducer in Colorectal Cancer 
Lewisy/b hapten (human), mAb (SC104) (preservative free)

Nampt/Visfatin Inhibitor – BULK Available 
CHS-828

Cell Permeable, Potent & Selective FABP4 Inhibitor 
BMS-309403

Endogenous Human ST2 Detection by FACS 
anti-ST2 (human), pAbs

New Potent Leptin Sensitizer 
Withaferin A

New Zika Virus Neutralizing Antibody 
anti-Zika Virus Envelope Protein (EIII domain), mAb (rec.) (neutralizing) (ZKA64) (preservative free)

Innate Immune Sensor of Influenza A Virus 
anti-ZBP1, mAb (Zippy-1)

Tingling-inducing Agent - BULK Available 
Pellitorine

New Activator of NLRP3  
N-Acetyl-D-glucosamine

Newly Described NLRP3 Inhibitor 
Prostaglandin E2 (PGE2)

Regulator of Adipose Tissue Thermogenesis 
Slit2 (C fragment) (human) (rec.)

Highly Active IL-33 Mutant Protein 
IL-33 (oxidation resistant) (human) (rec.) (His)

Potent and Selective PDE10A Inhibitor 
PF-2545920

Potent Activators of TRPV3 
Incensol, Incensol acetate & Serratol

NEW Toll-Like Receptor Family Antibodies 
TLR2 - TLR10 Monoclonal Antibodies

Unique mouse LRP5/6 mAb for FACS 
anti-LRP5/6, mAb (rec.) (Heldy-1-4)

Potent & Selective GAPDH Inhibitor 
Heptelidic acid

Potent, Selective & Competitive Cell Permeable Rasfarnesyltransferase Inhibitor 
Manumycin A & related Products

Agonistic LTβR Monoclonal Antibodies 
anti-LTβR (mouse), mAbs - Clones 3C8 & 4H8WH2

Potent BTLA-blocking Antibody - Available again! 
anti-BTLA (human), mAb (6F4)

AhR Agonist - Increases ILC3 in Gut Microbiota 
Indole-3-carbinol

Brown Adipose Tissue (BAT) Activator 
Miglitol

TRAIL-Rs – Important Cancer Regulators 
IHC and FACS competent TRAIL-Rs antibodies

Apaf-1 – Key Apoptosome Complex Factor 
Validated and specific Apaf-1 antibodies

Specific β-cell Proliferation Promoter 
GW311616A . hydrochloride

NEW Natural Anticancer Compounds 
Fridamycin A, B & Violacein

New Marker for Cardiology 
Nampt (Visfatin/PBEF) ELISA Kits

Unique Collagen Matrix Markers for ICC 
anti-Collagen Type 1 (3/4 fragment), pAbs

Inhibitor of FtsZ GTPase Activity 
(-)-Viriditoxin

Actin Polymerization Inhibitors in vitro and in vivo 
Latrunculin A+B

Selective Protease Inhibitors - BULK Available
Leupeptin, Pepstatin, Amastatin, Antipain...

A Multifunctional Adipokine Biomarker 
Nampt (Visfatin/PBEF) ELISA Kits

Exercise-induced Myokine Detection 
Irisin Competitive ELISA Kit

Potent LIM Kinase Inhibitor
BMS-3

Essential Axon Survival Factor – BULK available
NMNAT2 (human) (rec.) (His)

Orally Bioavailable Potent Inhibitor of JAK1 and JAK2
Ruxolitinib

Specific SREBP Inhibitor - BULK available
Betulin

Highly Active Untagged Proteins
IL-36α, IL-36β, IL-36γ, IL-36Ra

Rapid Apoptosis Inducer
Raptinal

Ionophore Antibiotics
Enniatins A/A1/B/B1

Potent Inhibitor of Human 5-lipoxygenase
Myxochelin A

For Enzymatic Assays & Inhibitor Screenings
IDO1 (human) Enzyme+Inhibitor Set

Potent Triazole IDO1 Inhibitor
MMG-0358

Inhibitor of PVR/CD155 Ligand
TIGIT (human):Fc (human)

New Negative Checkpoint Regulator
VISTA [B7-H5]: Fc Proteins

High Sensitive Asthma Biomarker Detection Kit
Periostin (human) ELISA Kit

Now Available - Produced in CHO Cells
Periostin (human) (rec.)

Potent Cell Permeable JAK3 Inhibitor
Tofacitinib

Potent Na+/K+-ATPase Inhibitor
Hellebrin

TurboELISA™ Kit - Results in less than 1 hour
Zinc-α-2-glycoprotein (human) TurboELISA Kit

Potent F-actin Modulators
Cucurbitacins B & E

Progranulin - Bulk Available
Recombinant human, mouse or rat Progranulin

Potent and Highly Selective BTK Inhibitor
Ibrutinib

Inflammasome Inhibitor for In Vivo Studies
MCC950 . sodium salt - BULK available

Unique - Produced in Mammalian Cells
Resistin (human) (rec.)

Highly Active IDO1 Enzyme for Inhibitor Screenings
IDO (human) (rec.) (His)

New UCP1-dependent Thermogenesis Inducer
CK2 Inhibitor 10

Biologically Active Cytokines
Human & Mouse IL-35

New Potent HDAC6 Inhibitors
Nexturastat B, Tubastatin A ...

Selective cell permeable MALT1 Inhibitor
Z-VRPR-FMK

Potent δ-Opioid Receptor Agonist - Bulk Available
SNC80

New Biomarker for Plasma Triglyceride Levels
anti-Betatrophin (human), pAb (IN108)

New Specific IL-38 Monoclonal Antibody
anti-IL-38, mAb (Nhat-1)

Unique Antibody for Metabolic Research
anti-MPC-2, mAb (JCM-1)

Highly Active IL-33 Protein
IL-33 (oxidation resistant) (human) (rec.) (untagged)

Antibiotic & Anti-inflammatory Natural Products
Chaetoglobosins

Tumor Suppressor & Anti-Inflammatory Protein - Bulk Available
CD137L, Soluble (mouse) (rec.)

Important Metabolism and Energy Regulator
Propionyl-L-carnitine . hydrochloride

Available Again - Also Bulk Quantity
BTLA (human), mAb (6F4)

Frequently cited Standard Apoptosis mAbs
anti-FLIP & anti-Caspase-8

Potent CDK1 / Cyclin B Inhibitor - Bulk Available
Alsterpaullone

GPVI Receptor Agonist for Platelet Receptor Studies
Convulxin

Functional Antibodies for in vivo Studies
anti-LTβR (mouse), mAbs

Potent and Selective CSF-1R Inhibitor
BLZ-945

New Skin Inflammation Antibodies
IL-36β (human)

Adipocyte Differentiation Inducer
IL-33 (mouse), mAb (rec.) (blocking) (Bondy-1-1)

Potent iNKT Stimulators
α-Galactosylceramide & Analogs

Potent & Fast Acting Antibiotic
Puromycin . dihydrochloride

New Inflammation Detection Set
IL-38 (human) Matched Pair Detection Set

New Skin Inflammation Detection Set
IL-36β (human) Matched Pair Detection Set

Potent Anti-inflammatory & Antidiabetic Agents
Amorfrutin A & B

Potent Multimeric TNF-α Proteins
High Activity TNF-α Proteins

Specific Antiviral Signaling Antibodies
NS3, NS5B, GPx8 Specific Antibodies

Potent Anti-Malaria Compound - BULK available
Borrelidin

Natural Inflammasome Inhibitors
Isoliquiritigenin
Arglabin

Netrin-1 BULK Available
Biological Active Netrin-1 Proteins

Ectodomain Shedding Protease Blocking Antibody
anti-ADAM17 (human), mAb (rec.) (blocking) (D1(A12))

Anti-Diabetic & NLRP3 Inflammasome Inhibitor
Glyburide

Anti-Obesity Agent & Potent Leptin Sensitizer
Celastrol

Biologically Active DLL4 Notch Ligand
DLL4 (human):Fc (human) (rec.)

Biologically Active DLK1 Notch Ligand
DLK1 (human):Fc (human) (rec.)

Novel Inhibitor of Aurora A Kinase
Tripolin B

Anticancer and Trypanocidal Compound
Asperphenamate

Specific Anti-Obesity Adipokine ZAG Detection
Zinc-α-2-glycoprotein (human) Matched Pair Detection Set

A Novel Hormone Regulating Metabolism
CTHRC1 (mouse) (rec.)

Potent and Selective NLRP3 Inflammasome Inhibitor
MCC950 . sodium salt

Standard FLIP Antibodies for Cell Death Research
anti-FLIP (human), mAb (NF6)
anti-FLIP, mAb (Dave-2)

Potent PD-1 & PDL-2 Immune Checkpoint Proteins
Human & Mouse Fc-Fusion Proteins – BULK Available

NF-kB p65 Suppressor
Sauchinone

Cell Permeable MKLP-2 Inhibitor
Paprotrain

New Potent Mitochondria-Derived AMPK Activator
MOTS-c

Potent Apoptosis Inducing Fas Antibody
anti-Fas (human), mAb (APO-1-3) (preservative free)

HIGH PURITY Thapsigargin - BULK available
Thapsigargin (high purity)

Novel Type of RNA Guanylyltransferase Inhibitor
Mycophenolic acid

C15 - Standard Human-specific Caspase-8 Antibody
anti-Caspase-8 (human) mAb (C15)

Potent B7-H4 Immune Checkpoint Proteins
Mouse Fc-Fusion Proteins – BULK Available

Potent Inducer of Actin Polymerization
Jasplakinolide

Potent Immunosuppressant
Triptolide

Potent CTLA-4 Immune Checkpoint Proteins
Human & Mouse Fc-Fusion Proteins – BULK Available

Photosensitizing Anticancer Agent
Hypericin

Cell Permeable Microtubule Inhibitor
Ilimaquinone

IL-36 – New Tools for Skin & Dendritic Cell Research
Antibodies, Proteins & Detection Sets

Anticoccidial Antibiotic
Oxyplicacetin

Potent Anti-Tuberculosis Antibiotic
Actinomycin X2

Active Adipogenesis Inhibitor
Jagged-1 (mouse):Fc (human) (rec.)

Novel Cold-Induced Adipokine
Neuregulin-4 (human) (rec.)

Live Imaging Acidotropic Fluorescent Dye
LysoGlow84™

Selective Cyclooxygenase-2 (COX-2) Inhibitor
Celecoxib

GPx8 - Cellular Substrate of HCV NS3-4A Protease
GPx8 (human), pAb (IN103)

Potent Inhibitor of Actin Polymerization
Cytochalasin H

Unique Anaphase Promoting Complex Inhibitor
Apcin

Potent mouse Angiopoietin-2 Blocking Antibody
Angiopoietin-2, mAb (rec.) (blocking) (Angy-2-1)

PI3K Class I, MKK3/6 & MKK4 Inhibitor
Eupatilin

Mitochondrial Respiration Inhibitor
Asteltoxin

NLRC3 - Negative Regulator of Innate Immunity
NLRC3 (mouse), mAb (Eowyn-1)

ZAG – An Adipokine Involved in Obesity
Zinc-α-2-glycoprotein (human) (rec.)
Zinc-α-2-glycoprotein (human), mAb (Zagy-1)
Zinc-α-2-glycoprotein (human), mAb (Zagy-2)

Marine Natural Products January 2015
Aloesin | Aloeresin A | Altersolanol A |
Helenalin | Manzamine A

Non-cytotoxic Melanogenesis Inhibitor
Aspochalasin I

Tubulin-Modification Specific Antibodies
α-Tubulin (acetylated), mAb (TEU318)
Polyglutamate chain (polyE), pAb (IN105)
Polyglutamylation Modification, mAb (GT335)

Hypersensitive Autoimmune Disease Biomarker
BAFF (human) ELISA Kit (hypersensitive)

BULK - Now Available from Stock!
Pellitorine & Indolactam V

Fungal Anticancer Compounds from BioViotica
Cephalochromin & Trypacidin

Unique mAPRIL Blocking Antibody
APRIL (mouse), mAb (rec.) (blocking) (Apry-1-3)

Standard Apoptosis Antibodies
Apaf-1 | BimL | Bmf | Caspase-2/-8/-12

Pan-PI3K Inhibitor
3-Methyladenine

Inhibitor of Isocitrate Lyase in Bacteria
Itaconic acid

News & Press Releases

Abcalis and AdipoGen Life Sciences Partner on Distributing Animal-free Recombinant Monoclonal and Multiclonal Antibodies on the Life Science Research Market

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Periostin Deficiency Reduces PD-1+ Tumor-associated Macrophages

A recent study published in Cell Reports describes the mechanism of action of Periostin in CRC. Periostin deficiency in tumor microenvironment (TME) significantly decreases the infiltration of PD-1+ TAMs (pro-tumoral) in colorectal cancer tissues of mice leading to suppression of tumor growth. Inhibition of both periostin and PD-1 significantly suppresses CRC progression and this approach could improve immune therapy efficacy in CRC in humans.

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Collaborating with
Ancell
BellBrook Labs		 BioViotica
Cayman Chemical		 Chemodex
Chimerigen		 Innaxon
JaICA		 RevMAb Biosciences
South Bay Bio		 SYNkinase
Vector Laboratories
Inflammasomes
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