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AdipoGen Life Sciences
BMS-3
95
CHF
CHF 95.00
In stock
AG-CR1-2901-M0055 mgCHF 95.00
AG-CR1-2901-M02525 mgCHF 380.00
| Product Details | |
|---|---|
| Synonyms | N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2- yl)cyclopropanecarboxamide |
| Product Type | Chemical |
| Properties | |
| Formula |
C17H12Cl2F2N4OS |
| MW | 429.3 |
| CAS | 1338247-30-5 |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Off-white solid. |
| Solubility | Soluble in DMSO (5mg/ml). |
| InChi Key | YBGGBHCJSAEIAS-UHFFFAOYSA-N |
| Smiles | ClC1=C(N2C(C3=CN=C(NC(C4CC4)=O)S3)=CC(C(F)F)=N2)C(Cl)=CC=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Potent LIMK (Lim kinase) inhibitor. Has IC50 values of 5nM and 6nM for LIMK1 and LIMK2, respectively.
Product References
- Phenyl-substituted pyrimidine compounds useful as kinase inhibitors: S.T. Wrobelski, et al.; WO2006084017 (2006)
- Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors: P. Ross-Macdonald, et al.; Mol. Cancer Ther. 7, 3490 (2008)