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Mini-Catalogs, Product Flyers, Insights and Wallcharts
Inflammasomes & Innate Immunity
Inflammasome Research - From Innate to Adaptive Immunity - Mini-Catalog Version with Weblinks - Released June 2023 |
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Innate Immunity - Focus Toll-like Receptors (TLR) Agonists - Mini-Catalog Version with Weblinks - Released November 2020 |
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Gasdermin D Signaling & Inflammasome Research - Insights Includes a Unique Tool to Measure Pyroptosis! For more information visit AdipoGen Life Sciences' landing page Gasdermin Signaling. |
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Key Inflammasome Research Tools - Product Flyer • Unique Antibodies: NLRP3 mAb (Cryo-2); Asc pAb; Caspase-1 (p10) mAb; Caspase-1 (p20) mAb (Casper-1) |
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Innaxon - Bringing Innate Immunity to Life - Product Flyer Innaxon develops and manufactures defined “Immunoceuticals” of the highest activity and purity for pre-clinical research and development applications for vaccine adjuvants and immunotherapy. Their unique biological and synthetic Toll-like Receptor (TLR) ligands (including MPLA, Lipid A, LPS and ODNs) are well-characterized and effective biological response modifiers of inappropriate or disproportionate immune responses and are provided as ready-to-use sterile solutions. Innaxon's product panel is exclusively available through AdipoGen Life Sciences. For an overview of Innaxon's entire panel of TLR Research Products please search this website. Released - October 2022 |
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Innaxon - Compounds powered by Lipodisq™ - Product Flyer Lipodisq™ are novel lipid/polymer nanoparticles that have been developed as mimics of naturally-occurring high-density lipoproteins (HDL). Innaxon's Actives in Lipodisq™ which are biosynthetic, detergent-free, water-soluble novel lipid/polymer nanoparticles with stable encapsulated active ingredients, that retain the biological activity with enhanced bioavailability. For an overview of Innaxon's entire Lipodisq™ panel please search this website. Released - October 2022 |
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NLRP3 Inflammasome Activation, Signaling & Regulation - Wallchart For details and products please see the Inflammasome Signaling Mini-Catalog! Released - October 2022 |
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Pattern Recognition Receptors Signaling - Wallchart For details and products please see the Innate Immunity Mini-Catalog! Released - September 2019 |
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B & T Cells Immune Regulation / Immune Checkpoints / Immuno-oncology
B-Xpander™ 2024 - Product Flyer B-Xpander™ is a potent enhanced Multimeric human CD40L cytokine, for B cell activation, B cell expansion (proliferation) and cell therapy applications. In-house production using a proprietary protocol and a characterized and certified CHO cell line allows the supply of the most active Multimeric human CD40L proteins in GMP-like format. Quality Features of B-Xpander™ include: For more information about AdipoGen Life Sciences' B-Xpander™ visit www.bxpander.com. Released - June 2024 |
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InVivoKines™ 2024 (2nd Edition) - Product Flyer InVivoKines™ are a new generation of recombinant fusion proteins for immunotherapeutic, preclinical and translational in vivo research, developed in-house by AdipoGen Life Sciences. InVivoKines™ are Fc-based fusion proteins using the Knobs-into-Holes (KIH) technology. Quality Features of InVivoKines™ include: For an overview of AdipoGen Life Sciences' entire panel of InVivoKines™ visit www.invivokines.com. Released - September 2024 |
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Immune Checkpoint Reagents: Focus on T Cells - Mini-Catalog Cancer immunotherapy (also called immuno-oncology) is the artificial stimulation of the immune system to treat cancer, improving the system's natural ability to fight cancer. Immune checkpoints are regulators of the immune system. These pathways are crucial for self-tolerance, which prevents the immune system from attacking cells indiscriminately. Inhibitory checkpoint molecules, such as CTLA-4, PD-1, PD-L1 or LAG-3 are targets for cancer immunotherapy due to their potential for use in multiple types of cancers. AdipoGen Life Sciences offers a broad panel of immune checkpoint reagents, including recombinant proteins, antibodies and ELISA Kits. For an overview of AdipoGen Life Sciences' entire panel of Immune Checkpoint Reagents please search this website. Version with Weblinks - Released November 2020 |
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TNF Superfamily - Key Cytokines in B & T cell Immuno-Regulation - Mini-Catalog TNFSF/TNFRSF together with the CD28-B7 family are two major co-signal pathways in T cell activation. CD28, ICOS, GITR, 4-1BB and OX40 pathways co-stimulate T cell activation. CTLA-4, PD-1, BTLA and CD160 pathways co-inhibit T cell activation. Includes: • TNFSF Overview Chart• APRIL & BAFF, CD40-CD40L, Fas-FasL and LTβ-HVEM-LIGHT-BTLA Pathways • TNF-α-TNF-β, CD137-CD137L and TRAIL-TRAIL-R Pathways • OX40-OX40L, GITR-GITRL, RANK-RANKL/OPG and other TNFSF Members Pathways • TNFSF and Cell Death Chapter • TNF Member Reactivity Chart
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Proteins with Enhanced Activity & Stability - Mini-Catalog AdipoGen Life Sciences specializes in the development of recombinant proteins that show enhanced activity and long half-life, produced in mammalian cells. Using proprietary in-house technologies together with established and published technologies, we engineer, develop and produce an innovative panel of recombinant proteins for different research fields including Cell Therapy Research. Includes: • TNF Ligands Multimeric Proteins• Monomeric Interleukins (KIH-Technology) • COMP-Proteins • Fc-Fusion Proteins (wild-type or non-lytic) • Proteins with Site-directed Mutations • Proteins for Improving ex vivo T Cell Expansion and for Preclinical Research
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Advanced Immune Regulation Reagents - Product Flyer Released - April 2019 Version with Weblinks - Released November 2020 |
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Autoimmune Disease Biomarkers APRIL & BAFF - Insights For more information visit AdipoGen Life Sciences' landing page Autoimmune Diseases Biomarkers. Latest Update - October 2021 |
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Ancell Corporation - Monoclonal Antibodies Overview - Product Flyer For an overview of the entire Ancell product portfolio please search this website. Released October 2022 |
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RevMAb Biosciences - Mutant-specific Rabbit Monoclonal Antibodies - Product Flyer For more information visit our RevMAb Biosciences landing page. Released - April 2021 |
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RevMAb Biosciences - Histone H3 Mutation Antibodies - Product Flyer For more information visit our RevMAb Biosciences landing page. Released - April 2021 |
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T Cell Immune Checkpoint - Wallchart For details and products please see the Immune Checkpoint Reagents Mini-Catalog! Released - March 2019 |
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TNF Superfamily Ligands & Receptors - Wallchart For details and products please see the TNF Superfamily Mini-Catalog 2022! Released June 2022 |
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Obesity & Metabolism
Obesity & Diabetes Research 2023 - Mini-Catalog For an overview of AdipoGen Life Sciences' entire panel of Obesity & Diabetes Products please search this website. |
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Immunometabolism Research - Focus Cell Metabolism & NAD+ Metabolism - Mini-Catalog This Mini-Catalog includes a cell metabolism signaling wallchart with relevant small molecule inhibitors. For an overview of AdipoGen Life Sciences' entire panel of Immunometabolism Research Reagents please search this website. |
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Erythroferrone (human) ELISA Kit - Insights • High Specificity For an overview of AdipoGen Life Sciences' panel of Iron Metabolism-related Products please search this website. Version with Weblinks - Released November 2020 |
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Cell Metabolism Signaling - Wallchart Overview of Glycolysis, TCA Cycle, Fatty Acid Oxidation, Fatty Acid Synthesis Pathway and Amino Acid Pathways, featuring the corresponding small molecule modulators. Released - January 2024 |
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Neuroinflammation
Neuroscience Research - Mini-Catalog |
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Progranulin - Marker of Neuroinflammation - Insights STANDARD - Progranulin [PGRN] ELISA Kit TAG-FREE - Progranulin Recombinant Proteins For more information visit AdipoGen Life Sciences' landing page on Progranulin. Released - January 2023 - Version with Weblinks |
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Interleukin-33 - Insights IL-33 is a nuclear-associated cytokine that is normally released by damaged or necrotic cells acting as an “alarmin”, an immediate indicator of tissue stress. IL-33 is a potent inducer of type 2 immune responses in the context of parasite infections and allergic asthma. New studies have also extended the biology of IL-33 with other functions: i) inducing brown and beige adipocyte thermogenesis and promoting insulin secretion by pancreatic islets; ii) facilitating Treg proliferation to suppress autoimmunity and to potentiate neurological recovery; and iii) exerting multiple roles in the brain. For more information visit AdipoGen Life Sciences' landing page on Interleukin-33 (in process). Released - January 2020 Version with Weblinks - Released November 2020 |
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SARS-CoV-2 / COVID-19 Research
COVID-19: Reagents for SARS-CoV-2/COVID-19 Research - Insights For an overview of AdipoGen Life Sciences' entire panel of COVID-19/SARS-CoV-2 Reagents see COVID-19. |
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Reagents for SARS-CoV-2/COVID-19 Research - Product Flyer For more information visit AdipoGen Life Sciences' landing page on COVID-19. Released - July 2020 |
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ELISA Kits & Assays
ELISA Kits for Key Biomarkers - Focusing on Emerging Research Fields - Mini-Catalog AdipoGen Life Sciences offers a broad range of Biomarker Assays. This Mini-Catalog includes the standard ELISA Kits for Adiponectin | ANGPTL3 | ANGPTL6 | APRIL | BAFF | Caspase-1 | CD40L | DLK1 | GPX1 | GPX3 | IL-36β | IL-36γ | IL-36Ra | IL-37 | IL-38 | Irisin | Nampt/Visfatin | Periostin | Progranulin (new mAb/mAb) | RBP4 | Vaspin | Zinc-α Glycoprotein, and also new Assays for SARS-CoV-2 | ACE2 | ACBP | Asprosin | B7-H3 | CD40L | Erythroferrone | FGL-1 | FNDC4 | Gasdermin D & E | ICOSL | IL-1β | PD-1 and PD-L1. Released - January 2023 - Includes Product URLs |
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ELISA Kits - Biomarker Assays for Preclinical & Diagnostic Research - Product Flyer AdipoGen Life Sciences ELISA Kits allow reproducible results with low inter- and intra-assay variation, show high sensitivity and can be used for a broad range of sample types. Released - September 2023 |
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Small Molecules / Biochemicals
Rare Antibiotics & Natural Products - Mini-Catalog AdipoGen Life Sciences offers a broad panel of >500 natural products, from bacterial, fungal, marine and plant sources. This panel includes known active and well-characterized natural products in combination with unusual and difficult to isolate compounds, which are unique to AdipoGen Life Sciences. All compounds are structurally determined, purified and analytically validated. Included in this panel are key standard research antibiotics, rare metabolites/antibiotics with new chemical structures (often only described once in literature and afterward lost to research), or old already forgotten substances for lead drug research, seeking new “antibiotics” with a new mode of actions and new molecular targets. For an overview of AdipoGen Life Sciences' entire panel of Rare Antibiotics & Unique Natural Products please search this website. |
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Chemodex - Fluorescent Reagents & Fine Chemicals - Mini-Catalog
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Modulators of Autophagy Signaling - Product Flyer AdipoGen Life Sciences offers a broad range of small molecules that can be used to modulate the autophagy process. This includes mTOR complex inhibitors and activators, pre-autophagosome (PAS) / initiation & nucleation modulators, autophagosome-lysosome fusion & degradation modulators and proteasome inhibitors. For an overview of AdipoGen Life Sciences' entire panel of Autophagy-related Products please search this website. Released - May 2014 |
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Miscellaneous
See here for an Overview of additional Biochemical Modulators Product Flyers | ||
Functional Antibodies - Mini-Catalog For an overview of AdipoGen Life Sciences' entire panel of Functional Antibodies please search this website. Version with Weblinks - Released November 2020 |
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The Tubulin Code: Posttranslational Modifications of Tubulin - Insights For more information visit AdipoGen Life Sciences' landing page on The Tubulin Code. Released - January 2020 Version with Weblinks - Released November 2020 |
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Manumycin A - Exosome Biogenesis Inhibitor AdipoGen Life Sciences offers a broad range of exosome biogenesis modulators (e.g. Manumycin A), standard exosome markers (e.g. CD9, CD63, CD81) and exosomal capturing/sorting biomarkers (Tim-4). Released - March 2024 |
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AdipoGen Life Sciences & South Bay Bio - Mini-Catalog • Highly Active Enzymes |
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The Ubiquitin-Proteasome System (UPS) - Product Flyer The ubiquitin-proteasome system (UPS) and the autophagic-lysosomal pathway are the two major degradation systems for both native and misfolded proteins in eukaryotic cells. Proteasome inhibition has therefore implications in a number of human diseases such as cancer, inflammation and ischemic stroke and is an important therapeutic target. Adipogen Life Sciences offers a broad panel of proteasome inhibitors, modulators and fluorogenic substrates, and a panel of proteasome complex proteins and kits. For an overview of AdipoGen Life Sciences' entire panel of "Proteasome-related Products" please search this website. Released - October 2022 |
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JaICA - Unique Oxidative Stress Markers - Product Flyer The Japan Institute for the Control of Aging (JaICA) develops and manufactures research reagents to detect oxidative stress markers for DNA oxidation, lipid oxidation, protein oxidation and antioxidants. The monoclonal antibodies and ELISA kits detect products of oxidative damage caused by reactive oxygen species. The JaICA products are well known in the research community and cited in many scientific publications. For an overview of JaICA's "Oxidative Markers" please search this website. Released - February 2014 |
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Notch Signaling Pathway - Mini-Catalog • Notch Receptors Notch1 & Notch2 Antibodies & Proteins • Canonical Notch Ligands: DLL1, DLL3, DLL4, Jagged-1 and -2 Antibodies & Proteins • Non-classical Notch Ligands: DLK1 and DLK2 Antibodies, Proteins and ELISA Kit • Non-confirmed Notch Ligand: DNER Antibodies & Proteins • Notch Target Hes1 • E3UBLs and DUBs • ADAM17 Blocking Antibody • Notch Processing/γ-Secretase Inhibitors Released - December 2022 |
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Notch Signaling Pathway - Activation, Signaling and Regulation - Wallchart For details and products please see the Notch Signaling Mini-Catalog! Released - May 2017 |
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