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AdipoGen Life Sciences
IL-38 (human) Matched Pair Detection Set
750
CHF
CHF 750.00
In stock
AG-46B-0007-KI011 SetCHF 750.00
Reagents for 5 x 96-well plates
Figure 1: Standard Curve
| Product Details | |
|---|---|
| Synonyms | Interleukin-1 Family Member 10 theta; IL-1F10; FIL1θ; FKSG75; IL-1HY2; IL1-θ; Interleukin-1 HY2; Interleukin-1 Receptor Antagonist FKSG75 |
| Product Type | Kit |
| Properties | |
| Application Set | Quantitative ELISA |
| Specificity | Recognizes human IL-38. |
| Crossreactivity | Human |
| Quantity | Contains sufficient materials to run ELISAs on 5 x 96-well plates. |
| Sensitivity | 20pg/ml |
| Range | 0.031 to 2ng/ml |
| Sample Type |
Cell Culture Supernatant Serum |
| Assay Type | Sandwich |
| Detection Type | Colorimetric |
| Kit Contains |
1 vial standard protein (1μg) (lyophilized) [STD] 1 vial coating antibody (270μl) [COAT] 1 vial detection antibody (60μl) [DET] 1 vial anti-IgG-HRP (10μg) (lyophilized) [HRP] |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Manual |
 Download PDF |
| MSDS |
Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
IL-38 (also called IL-1F10, and previously named IL1HY2, FIL1θ, or IL-1θ) is expressed in skin, tonsil, thymus, spleen, fetal liver, and salivary glands. The expression in a variety of immune tissues and similarity to IL-36Ra and IL-1Ra suggest a role of IL-38 in the inflammatory response. IL-38 binds to the IL-36R and exerts antagonistic effects similar to those of IL-36Ra.
Product References
- Interleukin-38 exerts antiinflammatory functions and is associated with disease activity in systemic lupus erythematosus: I. Rudloff, et al.; Arthr. Rheumatol. 67, 3219 (2015)
- Elevated plasma IL-38 concentrations in patients with acute ST-segment elevation myocardial infarction and their dynamics after reperfusion treatment: Y. Zhong, et al.; Med. Inflamm. 2015, ID490120 (2015)
- Aberrant expression of novel cytokine IL-38 and regulatory T lymphocytes in childhood asthma: M. Chu, et al.; Molecules 21, E933 (2016)
- Plasma interleukin-38 in patients with rheumatoid arthritis: W.D. Xu, et al.; Int. Immunopharmacol. 65, 1 (2018)
- Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression: F. Wang, et al.; Open Biol. 8, 180132 (2018)
- Interleukin-38 increases the insulin sensitivity in children with the type 2 diabetes: Y. Liu, et al.; Int. Immunopharm. 82, 106264 (2020)
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