Anhydrotetracycline hydrochloride

Specifications / Handling

More Information
Product Details
Synonyms	(4S,4aS,12aS)-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydro-2-tetracenecarboxamide hydrochloride (1:1)
Product Type	Chemical
Properties
Formula	C₂₂H₂₂N₂O₇ . HCl
MW	462.88
CAS	13803-65-1
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98% (HPLC)
Appearance	Yellow powder.
Solubility	Soluble in water or acetonitrile.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	XBSQEFHDCDFNJU-DXLATOOPSA-N
Smiles	[Cl-].[H][C@@]1(C2CC3=C(C)C4=C(C(O)=CC=C4)C(O)=C3C(=O)[C@]2(O)C(=O)C(C(N)=O)=C1O)[NH+](C)C
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

A tetracycline derivative exhibiting no antibiotic activity. A useful effector of tetracycline-dependent gene expression in bacterial expression systems.

Product References

(1) T. Sokoloski, et al.; J. Pharm. Sci., 66, 1159 (1977) | (2) M. Gossen & H. Bujard; Nucleic Acids Res. 21, 4411 (1993) | (3) L. Paemen, et al.; Biochem. Pharmacol., 5, 105 (1996) | (4) A.J. Gasparrini, et al.; Commun. Biol. 3, 241 (2020) | (5) E. Herbst, et al.; ACS Chem. Biol. 16, 1425 (2021) | (6) F. Schmidt, et al.; Science 376, 6594 (2022)

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