Chemodex

Tetracycline hydrochloride

CHF 27.00
In stock
CDX-T0096-G0055 gCHF 27.00
CDX-T0096-G02525 gCHF 81.00
More Information
Product Details
Synonyms 2-Naphthacenecarboxamide
Product Type Chemical
Properties
Formula C22H24N2O8 . HCl
MW 480.9
CAS 64-75-5
RTECS QI9100000
Source/Host Chemicals Synthetic
Purity Chemicals ≥99% (HPLC)
Appearance Yellow to orange powder.
Solubility Soluble in water (10 mg/ml), DMSO, methanol or 0.1 N HCl (10 mg/ml).
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key XMEVHPAGJVLHIG-FMZCEJRJSA-N
Smiles Cl.[H][C@@]12C[C@@]3([H])C(=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)C2N(C)C)C(=O)C1=C(O)C=CC=C1[C@@]3(C)O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic.

Product References

(1) J. Degenkolb, et al.; Antimicrob. Agents. Chemother. 35, 1591 (1991) | (2) D.N. Wilson; Crit. Rev. Biochem. Mol. Biol. 44, 393 (2009)

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