|Formula||C22H24N2O8 . HCl|
|Purity Chemicals||≥99% (HPLC)|
|Appearance||Yellow to orange powder.|
|Solubility||Soluble in water (10 mg/ml), DMSO, methanol or 0.1 N HCl (10 mg/ml).|
|Identity||Determined by NMR.|
|Declaration||Manufactured by Chemodex.|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Protect from light and moisture.
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic.
(1) J. Degenkolb, et al.; Antimicrob. Agents. Chemother. 35, 1591 (1991) | (2) D.N. Wilson; Crit. Rev. Biochem. Mol. Biol. 44, 393 (2009)