Tetracycline hydrochloride

Specifications / Handling

More Information
Product Details
Synonyms	2-Naphthacenecarboxamide
Product Type	Chemical
Properties
Formula	C₂₂H₂₄N₂O₈ . HCl
MW	480.9
CAS	64-75-5
RTECS	QI9100000
Source/Host Chemicals	Synthetic
Purity Chemicals	≥99% (HPLC)
Appearance	Yellow to orange powder.
Solubility	Soluble in water (10 mg/ml), DMSO, methanol or 0.1 N HCl (10 mg/ml).
Identity	Determined by NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	XMEVHPAGJVLHIG-FMZCEJRJSA-N
Smiles	Cl.[H][C@@]12C[C@@]3([H])C(=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)C2N(C)C)C(=O)C1=C(O)C=CC=C1[C@@]3(C)O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic.

Product References

(1) J. Degenkolb, et al.; Antimicrob. Agents. Chemother. 35, 1591 (1991) | (2) D.N. Wilson; Crit. Rev. Biochem. Mol. Biol. 44, 393 (2009)

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