(-)-Indolactam V

More Information
Product Details
Product Type	Chemical
Properties
Formula	C₁₇H₂₃N₃O₂
MW	301.4
CAS	90365-57-4
RTECS	UY8547000
Purity Chemicals	≥95%
Appearance	Off-white to light yellow solid.
Solubility	Soluble in DMSO or 100% ethanol.
Identity	Determined by ¹H-NMR.
Other Product Data	May contain traces of (+)-Indolactam V.
InChi Key	LUZOFMGZMUZSSK-LRDDRELGSA-N
Smiles	CC(C)[C@@H]1N(C)C2=CC=CC3=C2C(C[C@@H](CO)NC1=O)=CN3
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light.
Use/Stability	Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Product References

Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin: H. Fujiki, et al.; Gann 75, 866 (1984)
(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells: J. Heikkilä & K. Akerman; BBRC 162, 1207 (1989)
(-)-Indolactam V-induced mitogenesis in human fetal/neonatal and adult T cells: lower response of neonatal cells and possible regulatory role of monocytes in protein kinase C-mediated pathways: N. Papadogiannakis; Cell. Immunol. 162, 288 (1995)
A small molecule that directs differentiation of human ESCs into the pancreatic lineage: S. Chen, et al.; Nat. Chem. Biol. 5, 258 (2009)
Angiopoietins stimulate pancreatic islet development from stem cells: S.S. Karanth, et al.; Nature Sci. Rep. 11, 13558 (2021)

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