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AdipoGen Life Sciences
APRIL (human) ELISA Kit
610
CHF
CHF 610.00
In stock
AG-45B-0012-KI0196 wellsCHF 610.00
Figure 1: Specific quantitation of APRIL in human serum.
Method: Serum from a healthy patient is treated with TACI (human):Fc (human) (Prod. No. AG-40B-0079) coupled to NHS-Sepharose (or EDAR-Fc beads as control). APRIL levels were measured using the APRIL (human) ELISA Kit (Prod. No. AG-45B-0012).
Method: Serum from a healthy patient is treated with TACI (human):Fc (human) (Prod. No. AG-40B-0079) coupled to NHS-Sepharose (or EDAR-Fc beads as control). APRIL levels were measured using the APRIL (human) ELISA Kit (Prod. No. AG-45B-0012).
Figure 2: Standard curve
| Product Details | |
|---|---|
| Synonyms | A Proliferation Inducing Ligand; Tumor Necrosis Factor Ligand Superfamily Member 13; TNFSF13; TALL-2; CD256 |
| Product Type | Kit |
| Properties | |
| Application Set | Quantitative ELISA |
| Specificity |
Detects human APRIL in serum, plasma and cell culture supernatant. |
| Crossreactivity | Human |
| Quantity |
1 x 96 wells |
| Sensitivity | 1pg/ml |
| Range | 3.9 to 250pg/ml |
| Sample Type |
Cell Culture Supernatant Plasma Serum |
| Assay Type | Sandwich |
| Detection Type | Colorimetric |
| Other Product Data |
UniProt link O75888: APRIL (human) |
| Accession Number | O75888 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice |
After standard reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use. |
| Use/Stability | 12 months after the day of manufacturing. See expiry date on ELISA Kit box. |
| Documents | |
| Manual |
 Download PDF |
| MSDS |
Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells.
Product References
- APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans: D. Tsiantoulas, et al.; Nature 597, 92 (2021)
- Kinetics of free and ligand-bound atacicept in human serum: M. Eslami, et al.; Front. Immunol. 13, 1035556 (2022)
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