APRIL (human) ELISA Kit
Method: Serum from a healthy patient is treated with TACI (human):Fc (human) (Prod. No. AG-40B-0079) coupled to NHS-Sepharose (or EDAR-Fc beads as control). APRIL levels were measured using the APRIL (human) ELISA Kit (Prod. No. AG-45B-0012).
|Synonyms||A Proliferation Inducing Ligand; Tumor Necrosis Factor Ligand Superfamily Member 13; TNFSF13; TALL-2; CD256|
|Application Set||Quantitative ELISA|
Detects human APRIL in serum, plasma and cell culture supernatant.
1 x 96 wells
|Range||3.9 to 250pg/ml|
Cell Culture Supernatant
|Other Product Data||
UniProt link O75888: APRIL (human)
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||+4°C|
After standard reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Plate and reagents should reach room temperature before use.
|Use/Stability||12 months after the day of manufacturing. See expiry date on ELISA Kit box.|
|Product Specification Sheet|
APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells.
- APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans: D. Tsiantoulas, et al.; Nature 597, 92 (2021)
- Kinetics of free and ligand-bound atacicept in human serum: M. Eslami, et al.; Front. Immunol. 13, 1035556 (2022)