Ketanserin . tartrate

More Information
Product Details
Synonyms	3-[2-[4-(4-Fluorobenzoyl)-1-piperdinyl)ethyl]-2,4(1H,3H)-quinazolinedione tartrate
Product Type	Chemical
Properties
Formula	C₂₂H₂₂FN₃O₃ . C₄H₆O₆
MW	395.4 . 150.1
Merck Index	14: 5296
CAS	83846-83-7
RTECS	VA1411195
Purity Chemicals	≥98% (NMR)
Appearance	White to off-white solid.
Solubility	Soluble in DMSO; slightly soluble in water (4 mg/ml) or 100% ethanol (3 mg/ml).
InChi Key	KMTLTEVOQLMYRS-UHFFFAOYSA-N
Smiles	[CH2]C#CC.OOOOOO.FC1=CC=C(C=C1)C(=O)C1CCN(CCN2C(=O)NC3=CC=CC=C3C2=O)CC1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Product References

Vascular activity of ketanserin (R 41 468), a selective 5-HT2 receptor antagonist: J.M. van Nueten, et al.; Arch. Int. Pharmacodyn. Ther. 250, 328 (1981)
Ketanserin, a 5-HT2 antagonist, directly inhibits the ATP-sensitive potassium channel in mouse ventricular myocytes: J.M. Ju, et al.; J. Cardiovasc. Pharmacol. 47, 96 (2006)
The 5-HT2 antagonist ketanserin is an open channel blocker of human cardiac ether-à-go-go-related gene (hERG) potassium channels: Q. Li, et al.; Br. J. Pharmacol. 155, 365 (2008)

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