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Chemodex
N4-Acetylsulfamethoxazole
68
CHF
CHF 68.00
In stock
CDX-A0291-M01010 mgCHF 68.00
CDX-A0291-M05050 mgCHF 204.00
| Product Details | |
|---|---|
| Synonyms | N-{4-{[(5-Methyl-3-isoxazolyl)amino]sulfonyl}phenyl}acetamide; Sulfisomezole-N4-acetate; BRN 0285801; STX 606 |
| Product Type | Chemical |
| Properties | |
| Formula |
C12H13N3O4S |
| MW | 295.3 |
| CAS | 21312-10-7 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥99% (HPLC) |
| Appearance | White to off-white powder or crystals. |
| Solubility | Soluble in chloroform. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | GXPIUNZCALHVBA-UHFFFAOYSA-N |
| Smiles | CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=NOC(C)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
This is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole. Sulfamethoxazole is metabolized via acetylation, catalyzed by liver extramitochondrial N-acetyl transferases. Acetyl-Sulfamethoxazole is excreted in urine. Both compounds can be used as a probe for the molecular percentage enrichement of liver extramitochondrial acetyl-CoA. Acetyl-Sulfamethoxazole can also be used as a reference for sulfamethoxazole impurity and waste determination.
Product References
(1) T.B. Vree, et al.; Clin. Pharmacokinet. 3, 319 (1978) | (2) R.M. Hutabarat, et al.; Clin. Pharmacol. Ther. 49, 402 (1991) | (3) T. Heberer, et al.; Toxicol. Lett. 131, 5 (2002) | (4) T.A. Larsen, et al.; J. Biotechnol. 113, 295 (2004) | (5) K. Stein, et al.; Environ. Sci. Technol. 42, 6415 (2008)
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