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Chemodex
DIB-Cl
Product Details | |
---|---|
Synonyms | 4-(4,5-Diphenyl-imidazol-2-yl)benzoyl-chloride |
Product Type | Chemical |
Properties | |
Formula | C22H15ClN2O |
MW | 358.82 |
CAS | 162756-62-9 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥95% (HPLC) |
Appearance | White to off-white solid. |
Solubility | Soluble in acetonitrile. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | PHMRAWURTKPWFB-UHFFFAOYSA-N |
Smiles | ClC(=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=CC=C1)C1=CC=CC=C1 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) as reagent for amine labelling was used successfully for derivatization and fluorescence detection of enantiomers of methamphetamin and p-hydroxymethamphetamin, in urine samples. It has also been used for 3,4-Methylendioxy-N-methylamphetamin in blood, morpholine and orther compounds. DIB-Cl as a label was used on fluorescent derivatization some hydroxyl group containing endocrine disruptors, including bisphenol A (BPA), bisphenol B (BPB), bisphenol E (BPE), bisphenol F (BPF) and 4-nonylphenol (4-NP). DIB-Cl showed superior fluorescence intensity (FI) to other commercially available reagents, excellent stability in solution and high reactivity with primary and secondary amines under mild conditions.
(1) M. Wada et al.; Anal. Bioanal. Chem., 391(3), 1057 (2008) | (2) M. Tomita et al.; Biomed. Chromatogr., 20(12), 1380 (2006) | (3) Y. Sun et al.; Analyt. Sci. 17, 697 (2001) | (4) O. Al-Dirbashi et al.; J. Chtomatogr. B 712, 105 (1998)