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Chemodex
Sulforhodamine 101
Product Details | |
---|---|
Synonyms | SR 101; Sulforhodamine 640 |
Product Type | Chemical |
Properties | |
Formula | C31H30N2O7S2 |
MW | 606.71 |
CAS | 60311-02-6 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥99% (HPLC) |
Appearance | Green crystalline. |
Solubility | Soluble in water, methanol (1 mg/ml), ethanol, DMSO or DMF. |
Identity | Determined by NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | COIVODZMVVUETJ-UHFFFAOYSA-N |
Smiles | OS(=O)(=O)C1=CC(=C(C=C1)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S([O-])(=O)=O |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
Keep cool and dry. Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Sulforhodamine 101 is a non-fixable red fluorescent dye used as a specific marker for astrocytes and an activity-dependent probe for monitoring regulated exocytosis. In addition to labeling astrocytes, it also labels myelinating oligodendrocytes. Has been reported to affect excitability of neurons and should therefore be used with caution. Key precursor used for preparing rhodamine 101 sulfonyl chloride (also called Texas Red). Spectral data: λex 586 nm| λem 605 nm in H2O and λex 582-588 nm| λem 601-609 nm in pH7 buffer.
(1) W. Ulrich; Biotech. Histochem. 67, 73 (1992) | (2) H.H. Engelhard; Biotech. Histochem. 72, 1 (1997) | (3) A. Nimmerjahn, et al.; Nat. Methods 1, 31 (2004) | (4) A. Nimmerjahn & F. Helmchen; Cold Spring Harb. Protoc. 2012, 326 (2012) | (5) J. Kang, et al.; Neuroscience 169, 1601 (2010) | (6) R.A. Hill & J. Grutzendler; Nat. Methods 11, 1081 (2014)