Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
SynKinase
TGX-221
CHF 0.00
In stock
SYN-1089-M0011 mgCHF 92.00
SYN-1089-M0055 mgCHF 149.00
SYN-1089-M01010 mgCHF 248.00
SYN-1089-M05050 mgCHF 766.00
SYN-1089-M100100 mgINQ
Product Details | |
---|---|
Synonyms | TGX221 |
Product Type | Chemical |
Properties | |
Formula | C21H24N4O2 |
MW | 364.5 |
CAS | 663619-89-4 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | CPRAGQJXBLMUEL-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
TGX221 is a potent, cell permeable ATP-competitive inhibitor of PI3K, with selectivity for the p110β isoform (IC(50) of 50nM).
Product References
- Advantages of a selective beta-isoform phosphoinositide 3-kinase antagonist, an anti-thrombotic agent devoid of other cardiovascular actions in the rat: S.A. Sturgeon, et al.; Eur. J. Pharmacol. 587, 209 (2008)