MPI-0479605 hydrochloride

More Information
Product Details
Synonyms	MPI0479605
Product Type	Chemical
Properties
Formula	C₂₂H₂₉N₇O . HCl
MW	407.5 . 36.5
CAS	1246529-32-7 (free base)
Purity Chemicals	≥95%
Appearance	Solid.
Solubility	Soluble in DMSO.
Declaration	Manufactured by SynKinase.
Other Product Data	Target: MEK - MEK5 \| Kinase Group: STE \| Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	BYBIFMLUJUNGNX-UHFFFAOYSA-N
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

MPI-0479605 inhibits TTK kinase activity in vitro with an IC(50) of 4nM.

Product References

Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1: K.D. Tardif, et al.; Mol. Cancer Ther. 10, 2267 (2011)

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