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AdipoGen Life Sciences
anti-DLL1 (human), pAb
390
CHF
CHF 390.00
In stock
AG-25A-0079-C100100 µgCHF 390.00
Figure 1: Western blot analysis using anti-DLL1 (human), pAb (Prod. No. AG-25A-0079) at 1:2'000 dilution.
1: Human DLL1 Fc-protein.
2: Human DLL1 (FLAG®-tagged)
3: Transfected human DLL1 cell lysate (HEK 293).
4: Primary human pancreatic mesenchymal cell lysate.
5: Mock transfected HEK 293 cell lysate.
6: Human Progranulin (FLAG®-tagged) (negative control).
1: Human DLL1 Fc-protein.
2: Human DLL1 (FLAG®-tagged)
3: Transfected human DLL1 cell lysate (HEK 293).
4: Primary human pancreatic mesenchymal cell lysate.
5: Mock transfected HEK 293 cell lysate.
6: Human Progranulin (FLAG®-tagged) (negative control).
| Product Details | |
|---|---|
| Synonyms | Delta-like Protein 1; Delta1 |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rat |
| Immunogen/Antigen | Recombinant human DLL1. |
| Application |
ELISA: (direct and indirect: 1:2’000-1:5’000) Western Blot: (1:2’000-1:5’000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application. |
| Crossreactivity | Human |
| Specificity | Recognizes human DLL1. Detects a band of ~68kDa by Western blot. |
| Purity Detail | Protein A-affinity purified. |
| Concentration | 1mg/ml |
| Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
Product References
- Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche: J.A. Kim, et al.; Stem Cells 27, 1318 (2009)
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