anti-PARP-2 [ARTD2] (mouse), pAb antibody

Specifications / Handling

More Information
Product Details
Synonyms	Poly(ADP-ribose) Polymerase 2; ADP-ribosyltransferase Diphtheria Toxin-like 2; NAD(+) ADP-ribosyltransferase 2
Product Type	Polyclonal Antibody
Properties
Source/Host	Rabbit
Immunogen/Antigen	Recombinant mouse PARP-2 [ARTD2] (aa 1-207).
Application	Immunocytochemistry: 1:500-1:1'000 Immunohistochemistry: 1:500-1:1'000 Immunoprecipitation: 2μl per 100μg nuclear extract Western Blot: 1:2'000-1:5'000 Optimal conditions must be determined individually for each application.
Crossreactivity	Human Mouse
Specificity	Recognizes mouse PARP-2. Cross-reacts weakly with human PARP-2.
Formulation	Liquid. Contains 0.1% sodium azide.
Isotype Negative Control	Rabbit IgG
Other Product Data	UniProt ID O88554: PARP-2 (mouse)
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

PARP-2 (ARTD2) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Call	+41 61 926 6040
Fax	+41 61 926 6049