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AdipoGen Life Sciences
ANGPTL3 (mouse/rat) Dual ELISA Kit
640
CHF
CHF 640.00
In stock
AG-45A-0015YEK-KI0196 wellsCHF 640.00
Figure 1: Standardcurve
| Product Details | |
|---|---|
| Synonyms | Angiopoietin-like Protein 3; Angiopoietin-5; ANG-5 |
| Product Type | Kit |
| Properties | |
| Application Set | Quantitative ELISA |
| Specificity | Detects mouse and rat ANGPTL3. Does not cross-react with human ANGPTL3, mouse ANGPTL4 or human ANGPTL4. |
| Crossreactivity |
Mouse Rat |
| Quantity | 1 x 96 wells |
| Sensitivity | 15pg/ml |
| Range | 0.016 to 1ng/ml |
| Sample Type |
Cell Culture Supernatant Plasma Serum |
| Assay Type | Sandwich |
| Detection Type | Colorimetric |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice |
After standard reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use. |
| Use/Stability | 12 months after the day of manufacturing. See expiry date on ELISA Kit box. |
| Documents | |
| Manual |
 Download PDF |
| MSDS |
Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose, and energy metabolism. ANGPTL3 plasma levels are increased in a mouse model of diabetes mellitus.
Product References
- Atypical angiopoietin-like protein that regulates ANGPTL3: F. Quagliarini, et al.; PNAS 109, 19751 (2012)
- Hepatic ANGPTL3 regulates adipose tissue energy homeostasis: Y. Wang, et al.; PNAS 112, 11630 (2015)
- A vital role for Angptl3 in the PAN-induced podocyte loss by affecting detachment and apoptosis in vitro: R. Dai, et al.; BMC Nephrol. 16, 38 (2015)
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