Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
SynKinase
GW-441756
CHF 0.00
In stock
SYN-1044-M0011 mgCHF 85.00
SYN-1044-M0055 mgCHF 142.00
SYN-1044-M01010 mgCHF 163.00
SYN-1044-M05050 mgCHF 646.00
SYN-1044-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | GW441756 |
| Product Type | Chemical |
| Properties | |
| Formula | C17H13N3O |
| MW | 275.3 |
| CAS | 504433-23-2 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: TrkA | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | NXNQLECPAXXYTR-LCYFTJDESA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Product References
- Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway: T.A. Kudo, et al.; Genes Cells 16, 1121 (2011)
Related Products
