The store will not work correctly when cookies are disabled.
Cookie Policy:This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Potent phenolic antioxidant found in grapes and red wine [1, 19].
Eicosanoid synthesis and platelet aggregation inhibitor [2].
Estrogen receptor agonist [3].
Chemopreventive [4, 15].
Specific inhibitor of cyclooxygenase-1 (COX-1) [4].
Anti-inflammatory [4, 21].
Ribonucleotide reductase and DNA synthesis [5].
Arrests cell cycle at S/G2 phase [6, 23].
Anticancer and antiproliferative compound [7, 16].
Apoptosis inducer [8, 23].
Protein kinase D inhibitor. Does not inhibit PKC [9].
Autophagy inducer [10, 23].
Potent SIRT1 (sirtuin 1) activator [11, 22].
Neuroprotective [12, 18].
Adipogenesis inhibitor [13].
PGC-1α activator [14].
Sonic hedgehog (Shh) signaling pathway modulator. Gli1 mRNA expression inhibitor. Downregulates Gli transcriptional activity [17].
Cardioprotective [19, 21].
Anti-diabetic [20].
Senescence modulator. Extends lifespan [22].
Product References
Antioxidant activity of resveratrol in red wine: N.J. Miller & C. Rice-Evans; Clin. Chem. 41, 1789 (1995)
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease: C.R. Pace-Asciak, et al.; Clin. Chem. Acta 235, 207 (1995)
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor: B.D. Gehm, et al.; PNAS 94, 14138 (1997)
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes: M. Jang, et al.; Science 275, 218 (1997)
Resveratrol, a remarkable inhibitor of ribonucleotide reductase: M. Fontecave, et al.; FEBS Lett. 421, 277 (1998)
Resveratrol arrests the cell division cycle at S/G2 phase transition: F.D. Ragione, et al.; BBRC 250, 53 (1998)
Antiproliferative effect of synthetic resveratrol on human breast epithelial cells: O.P. Mgbonyebi, et al.; Int. J. Oncol. 12, 865 (1998)
Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells: J. Dörrie, et al.; Cancer Res. 61, 4731 (2001)
Inhibition of protein kinase D by resveratrol: R.S. Haworth & M. Avkiran; Biochem. Pharmacol. 62, 1647 (2001)
Resveratrol-induced autophagocytosis in ovarian cancer cells: A.W. Jr. Opipari, et al.; Cancer Res. 64, 696 (2004)
Mechanism of Human SIRT1 Activation by Resveratrol: MT. Borra, et al.; J. Biol. Chem. 280, 17187 (2005)
Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad?: P. Saiko, et al.; Mutat. Res. 658, 68 (2008)
Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes: S. Rayalam, et al.; Phytother. Res. 22, 1367 (2008)
Resveratrol exerts pharmacological preconditioning by activating PGC-1α: L. Tan, et al.; Med. Hypotheses 71, 664 (2008)
Resveratrol and chemoprevention: S.K. Goswami & D.K. Das; Cancer Lett. 284, 1 (2009) (Review)
Resveratrol: Biological and pharmaceutical properties as anticancer molecule: T.C. Hsieh & J.M. Wu; Biofactors 36, 360 (2010) (Review)
Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer: A. Slusarz, et al.; Cancer Res. 70, 3382 (2010)
Neuroprotective properties of resveratrol in different neurodegenerative disorders: D. Albani, et al.; Biofactors 36, 370 (2010) (Review)
Resveratrol: a cardioprotective substance: J.M. Wu & T.C. Hsieh; Ann. N. Y. Acad. Sci. 1215, 16 (2011) (Review)
Anti-diabetic effects of resveratrol: T. Szkudelski & K. Szkudelska; Ann. N. Y. Acad. Sci. 1215, 34 (2011) (Review)
Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease: A. Csiszar; Ann. N. Y. Acad. Sci. 1215, 117 (2011) (Review)
Resveratrol and life extension: B. Agarwal & J.A. Baur; Ann. N. Y. Acad. Sci. 1215, 138 (2011) (Review)
Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe: D. Delmas, et al.; Curr. Med. Chem. 18, 1100 (2011) (Review)
Download PDF 
