AdipoGen Life Sciences
| Product Details | |
|---|---|
| Synonyms | 5-L-Leucine-Malformin A; BRN 4896114; (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-] |
| Product Type | Chemical |
| Properties | |
| Formula |
C23H39N5O5S2 |
| MW | 529.7 |
| CAS | 59926-78-2 |
| Source/Host Chemicals | Synthetic. Originally isolated from Aspergillus niger FKI-2342. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in DMSO, methanol, ethanol or chloroform. Insoluble in water. |
| Other Product Data |
Malformin C is a bicyclic pentapeptide containing L-leucine, D-isoleucine, L-valine, and two D-cysteines coupled with a disulfide-bond bridge. Malformins A1 and C, originally isolated from the culture broth of Aspergillus niger FKI-2342, were found to abrogate the bleomycin-induced G2 arrest in Jurkat cells with IC50 values of 480nM and 0.9nM, respectively. Malformins may be promising candidates as anti-cancer agents. |
| InChi Key | TZODYIWCRGWHQB-TZNCUMHOSA-N |
| Smiles | CC(C)C[C@@H]1NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H]2CSSC[C@@H](NC1=O)C(=O)N2)C(C)C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
