AdipoGen Life Sciences

Amauromine

CHF 75.00
In stock
AG-CN2-0113-C250250 µgCHF 75.00
AG-CN2-0113-M0011 mgCHF 225.00
More Information
Product Details
Synonyms Antibiotic FR 900220; WF 6237
Product Type Chemical
Properties
Formula

C32H36N4O2

MW 508.7
CAS 88360-87-6
RTECS UQ3987000
Source/Host Chemicals Isolated from Gymnascella sp.
Purity Chemicals ≥95% (HPLC)
Appearance Brown solid.
Solubility Soluble in DMSO, ethanol or methanol.
InChi Key VKEAHNPKYMHYJJ-UHFFFAOYSA-N
Smiles CC(C)(C=C)C12CC3N(C1NC1=C2C=CC=C1)C(=O)C1CC2(C(NC4=C2C=CC=C4)N1C3=O)C(C)(C)C=C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Antibiotic.
  • Hypotensive vasodilator.
  • Calcium channel antagonist.
  • Potent and selective CB1 receptor antagonist.
Product References
  1. Amauromine, a new vasodilator. Taxonomy, isolation and characterization: S. Takase, et al.; J. Antibiot. (Tokyo) 37, 1320 (1984)
  2. Structure of amauromine, a new alkaloid with vasodilating activity produced by sp: S. Takase, et al.; Tetrahedron Lett. 25, 4673 (1984)
  3. Structure of amauromine, a new hypotensive vasodilator produced by sp: S. Takase, et al.; Tetrahedron 41, 3037 (1985)
  4. Total synthesis of amauromine: S. Takase, et al.; Tetrahedron Lett. 26, 847 (1985)
  5. Novoamauromine and ent-Cycloechinulin: two new diketopiperazine derivatives from Aspergillus novofumigatus: K. Ishikawa, et al.; Chem. Pharm. Bull. 58, 717 (2010)
  6. Identification of a Potent and Selective Cannabinoid CB1 Receptor Antagonist from Auxarthron reticulatum: M.F. Elsebai, et al.; ACS Med. Chem. Lett. 2, 866 (2011)
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