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AdipoGen Life Sciences
Aranorosin
75
CHF
CHF 75.00
In stock
AG-CN2-0114-C250250 µgCHF 75.00
AG-CN2-0114-M0011 mgCHF 225.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C23H33NO6 |
| MW | 419.5 |
| CAS | 117184-53-9 |
| RTECS | JR1550000 |
| Source/Host Chemicals | Isolated from Gymnascella sp. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in DMSO, ethanol or methanol. |
| InChi Key | JHTWWPWUODMKEO-PHJKOLFRSA-N |
| Smiles | CCCCCC[C@H](C)\C=C(/C)\C=C\C(=O)N[C@@H]1C[C@]2(O[C@@H]1O)[C@H]1O[C@H]1C(=O)[C@H]1O[C@@H]21 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic [1, 2].
- Antibacterial [1-6].
- Antifungal [1-6].
- Anticancer compound [3, 4].
- Inhibits anti-apoptotic functions regulated by Bcl-2 [7].
- Circumvents arbekacin (ABK)-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2'') [8].
Product References
- Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. I. Taxonomy, fermentation, isolation, chemical and biological properties: K. Roy, et al.; J. Antibiot. (Tokyo) 41, 1780 (1988)
- Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. II. Structure elucidation: H.W. Fehlhaber, et al.; J. Antibiot. (Tokyo) 41, 1785 (1988)
- Structure of aranorosin, a new antibiotic of a novel skeletal type: H.W. Fehlhaber, et al.; JACS 110, 8242 (1988)
- Stereoselective synthesis of the functionalized spirocyclic core of aranorosin: P. Wipf & Y. Kim; J. Org. Chem. 58, 1649 (1993)
- Structure of a model for the aranorosin nucleus: R. C. Haltiwanger, et al.; Acta Cryst. C 50, 274 (1994)
- Structure-activity relationships of new aranorosin analogs to antifungal activity: E.K. Vijayakumar, et al.; J. Antibiot. (Tokyo) 51, 522 (1998)
- Aranorosin and a novel derivative inhibit the anti-apoptotic functions regulated by Bcl-2: T. Nakashima, et al.; BBRC 377, 1085 (2008)
- Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2''): T. Suga, et al.; J. Antibiot. (Tokyo) 65, 527 (2012)
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