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AdipoGen Life Sciences
Aranorosinol B
230
CHF
CHF 230.00
In stock
AG-CN2-0494-M0011 mgCHF 230.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C26H39NO7 |
| MW | 477.6 |
| CAS | 145147-05-3 |
| Source/Host Chemicals | Isolated from Phoma sp. |
| Purity Chemicals | ≥94% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in DMSO, ethanol or methanol. |
| Identity | Determined by 1H-NMR and MS. |
| InChi Key | YFJWRMZGLWVCSQ-ZXTVQVQKSA-N |
| Smiles | CCCCCC[C@@H](C)/C=C(C)/C=C/C(N[C@@H]1C(O)O[C@]2([C@H](O3)[C@H]3C(CC(C)=O)(O)[C@H]4[C@@H]2O4)C1)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic. Moderate antibacterial and antifungal agent.
- Inhibits the autophosphorylation of histidine kinase WalK/YycG. The WalK/WalR (aka YycG/YycF) two-component system is indispensable in the signal transduction pathway for the cell-wall metabolism/synthesis.
Product References
- Aranorosinol A and Aranorosinol B, two new metabolites from Pseudoarachniotus roseus: production, isolation, structure elucidation and biological properties: K. Roy, et al.; J. Antibiot. 45, 1592 (1992)
- Isolation and characterization of inhibitors of the essential histidine kinase, YycG in Bacillus subtilis and Staphylococcus aureus: T. Watanabe, et al.; J. Antibiot. 56, 1045 (2003)
- Cytotoxic acyl amides from the soil fungus Gymnascella dankaliensis: L. Hammerschmidt, et al.; Bioorg. Med. Chem. 23, 712 (2015)
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