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AdipoGen Life Sciences
Aerothionin
180
CHF
CHF 180.00
In stock
AG-CN2-0453-M0011 mgCHF 180.00
| Product Details | |
|---|---|
| Synonyms | NSC177380 |
| Product Type | Chemical |
| Properties | |
| Formula |
C24H26Br4N4O8 |
| MW | 818.1 |
| CAS | 28714-26-3 |
| Source/Host Chemicals | Isolated from Suberea sp. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Colorless to white adhered film. |
| Solubility | Soluble in DMSO or 100% ethanol. |
| Identity | Determined by 1H-NMR and MS. |
| InChi Key | BJWQSQOWGBUSFC-UWXQAFAOSA-N |
| Smiles | COC1=C(Br)[C@H](O)[C@]2(CC(=NO2)C(=O)NCCCCNC(=O)C2=NO[C@@]3(C2)C=C(Br)C(OC)=C(Br)[C@@H]3O)C=C1Br |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Protect from light. Protect from moisture. |
| Use/Stability |
Stable for at least 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Anti-mycobacterial.
Product References
- Aerothionin, a tetrabromo-compound from Aplysina aerophoba and Verongia thiona: E. Fattorusso, et al.; J. Chem. Soc. D: Chem. Commun. 12, 752 (1970)
- Aerothionin and homoaerothionin: Two tetra bromo spirocyclohexadienylisoxazoles from Verongia sponges: K. Moody, et al.; J. C. S. Perkin Trans. I, 18 (1972)
- An x-ray study of aerothionin from Aplysina fistularis: J.A. McMillan, et al.; Tetrahedron Lett. 22, 39 (1981).
- Chemistry of sponges, VII. 11,19-Dideoxyfistularin 3 and 11-Hydroxyaerothionin, bromotyrosine derivatives from Pseudoceratina durissima: M.R. Kernan & R.C. Cambie; J. Nat. Prod. 53, 615 (1990)
- Chemistry of Verongida sponges, II. Constituents of the Caribbean sponge Aplysina fistularis forma fulva: P. Ciminiello, et al.; J. Nat. Prod. 57, 705 (1994)
- Aerothionin, a bromotyrosine derivative with antimycobacterial activity from the marine sponge Aplysina gerardogreeni (Demospongia): R. Encarnacion-Dimayuga, et al.; Pharm. Biol. 41, 384 (2003)
- Asymmetric synthesis of aerothionin, a marine dimeric spiroisoxazoline natural product, employing optically active spiroisoxazoline derivative: T. Ogamino, et al.; Tetradedron Lett. 47, 727 (2006)
- Bioactive constituents from the marine crinoid Himerometra magnipinna: N. Shao, et al.; J. Nat. Prod. 70, 869 (2007)
- Bioactive brominated metabolites from the Red Sea sponge Suberea mollis: M.I. Abou-Shoer, et al.; J. Nat. Prod. 71, 1464 (2008)
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