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AdipoGen Life Sciences
Butyrolactone II
170
CHF
CHF 170.00
In stock
AG-CN2-0423-C500500 µgCHF 170.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C19H16O7 |
| MW | 356.3 |
| CAS | 87414-44-6 |
| Source/Host Chemicals | Isolated from Aspergillus sp. |
| Purity Chemicals | ≥97% (HPLC) |
| Appearance | Brown amorphous solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Identity | Determined by 1H-NMR and MS. |
| InChi Key | AEKPZNDJHWFONI-UHFFFAOYSA-N |
| Smiles | COC(=O)[C@]1(CC2=CC=C(O)C=C2)OC(=O)C(O)=C1C1=CC=C(O)C=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Protect from light. Protect from moisture. |
| Use/Stability |
Stable for at least 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic. Weak cytotoxic towards bacterial and cancer cell lines [1-3].
- 5-Lipoxygenase (5-LOX) inhibitor [4, 5].
- Shows DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavening activity [5].
Product References
- Metabolities of the Strain IFO 8835: N. Kiriyama, et al.; Chem. Pharm. Bull. 25, 2593 (1977)
- Biosynthesis of butyrolactone derivatives isolated from strains IFO 8835 and 4100: K. Nitta, et al.; Chem. Pharm. Bull. 31, 1528 (1983)
- Butyrolactones from Aspergillus terreus: K.V. Rao, et al.; Chem. Pharm. Bull. 48, 559 (2000)
- Butyrolactones, inhibitors of 5-lipoxygenase from fungal metabolites: F.S. Wang, et al.; J. Chin. Pharm. Sci. 19, 251 (2010)
- Soybean lipoxygenase inhibitory and DPPH radical-scavenging activities of aspernolide A and butyrolactones I and II: Y. Sugiyama, et al.; Biosci. Biotechnol. Biochem. 74, 881 (2010)
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