AdipoGen Life Sciences

1233B

CHF 75.00
In stock
AG-CN2-0112-C250250 µgCHF 75.00
AG-CN2-0112-M0011 mgCHF 225.00
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Product Details
Synonyms L 660282; L 660,282; 12-Hydroxy-13-(hydroxymethyl)-3,5,7-trimethyl-2,4-tetradecadiene-1,14-dioic acid
Product Type Chemical
Properties
Formula

C18H30O6

MW 342.4
CAS 34668-61-6
Source/Host Chemicals Isolated from Scopulariopsis sp.
Purity Chemicals ≥95% (HPLC)
Appearance Off-white solid.
Solubility Soluble in DMSO, ethanol or methanol.
InChi Key QFZISQBFEIXWDM-ZXIXUIEIBL
Smiles C[C@H](CCCCC(O)[C@@H](CO)C(O)=O)C\C(C)=C\C(\C)=C\C(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Hydroxy-acid of antibiotic 1233A.
  • Antibiotic.
  • Antibacterial.
  • Shows low toxicity on zebrafish embryos (48h, 10 μM).
Product References
  1. Antibiotic 1233A: a fungal-lactone: D.C. Aldrige, et al.;  J. Chem. Soc. Perkin 23, 3888 (1971)
  2. Inhibition of Hydroxymethylglutaryl-Coenzyme A Synthase by L-659,699: M.D. Greenspan, et al.; PNAS 84, 7488 (1987)
  3. Fungi from marine sponges: diversity, biological activity and secondary metabolites: U. Hoeller, et al.; Mycol. Res. 104, 1354 (2000)
  4. New Bis-Alkenoic Acid Derivatives from a Marine-Derived Fungus Fusarium solani H915: S.Z. Liu, et al.; Mar. Drugs 16, 483 (2018)
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