AdipoGen Life Sciences

Bisindolylmaleimide III

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AG-CR1-0112-M0011 mgCHF 80.00

AG-CR1-0112-M0055 mgCHF 240.00

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Product Details
Synonyms	BIM III
Product Type	Chemical
Properties
Formula	C₂₃H₂₀N₄O₂
MW	384.4
CAS	137592-43-9
Purity Chemicals	≥98% (NMR)
Appearance	Red solid.
Solubility	Soluble in methanol or DMSO.
Identity	Determined by ¹H-NMR.
InChi Key	APYXQTXFRIDSGE-UHFFFAOYSA-N
Smiles	NCCCN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CNC2=C1C=CC=C2
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Product References

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991)
Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides: P.D. Davis, et al.; J. Med. Chem. 35, 177 (1992)
Protein kinase C inhibitors; structure-activity relationships in K252c- related compounds: S. Fabre & M. Prudhomme; Bioorg. Med. Chem. 1, 193 (1993)
Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors: D. Brehmer, et al.; Mol. Cell Proteomics 3, 490 (2004)
An immuno-chemo-proteomics method for drug target deconvolution: C. Saxena, et al.; J. Proteome Res. 7, 3490 (2008)

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