BioViotica

Palmarumycin C3

CHF 155.00
In stock
BVT-0078-M0011 mgCHF 155.00
BVT-0078-M0055 mgCHF 470.00
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Product Details
Synonyms (1a'R,7a'S)-3',6'-Dihydroxy-1a'H-spiro[naphtho[1,8-de][1,3]dioxine-2,2'-naphtho[2,3-b]oxiren]-7'(7a'H)-one
Product Type Chemical
Properties
Formula

C20H12O6

MW 348.3
CAS 159934-11-9
Source/Host Chemicals Isolated from Sphaeropsidales sp.
Purity Chemicals ≥97% (HPLC)
Appearance Yellow to green solid.
Solubility Soluble in DMSO, dichloromethane, acetone or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key BDXBHYOFNNANPN-RTBURBONSA-N
Smiles OC1=CC=C(O)C2=C1C(=O)[C@H]1O[C@H]1C21OC2=CC=CC3=C2C(O1)=CC=C3
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Rasfarnesyltransferase inhibitor.
  • Antifungal, antibacterial and herbicidal.
  • Structurally unique natural products. The basic structure of palmarumycin C1 can be modified by a number of hydroxylation, oxygenation, dehydrogenation and chlorination steps.
  • Antioxidant.
Product References
  1. Biologically Active Metabolites from Fungi, 4. Palmarumycins CP1-CP4 from Coniothyrium palmarum: Isolation, structure elucidation, and biological activity: K. Krohn, et al.; Liebigs Ann. Chem. 1994, 1093 (1994)
  2. Biologically Active Metabolites from Fungi, 5. Palmarumycins C1-C16 from Coniothyrium sp.: Isolation, structure elucidation, and biological activity: K. Krohn, et al.; Liebigs Ann. Chem. 1994, 1099 (1994)
  3. Secondary metabolites by chemical screening, 42 Cladospirones B to I from Sphaeropsidales sp. F-24'707 by variation of culture conditions: H.B. Bode, et al.; Eur. J. Org. Chem. 2000, 3185-3193 (2000)
  4. Unified route to the palmarumycin and preussomerin natural products. Enantioselective synthesis of (-)-preussomerin G: A.G. Barrett, et al.; J. Org. Chem. 67, 2735-2750 (2002)
  5. Natural products derived from naphthalenoid precursors by oxidative dimerization: K. Krohn; Prog. Chem. Org. Nat. Prod. 85, 1-49 (2003) (Review)
  6. Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C2 and C3 Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12: Y. Mou, et al.; Molecules 18, 15587 (2013)
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