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BioViotica
Isatropolone A
145
CHF
CHF 145.00
In stock
BVT-0080-M0011 mgCHF 145.00
BVT-0080-M0055 mgCHF 430.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C24H24O9 |
| MW | 456.5 |
| Source/Host Chemicals | Isolated from Streptomyces rubiginosohelvolus Gö66. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Orange powder. |
| Solubility | Soluble in DMSO, chloroform or dichloromethane. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | GPTONKSPQNETHU-DLIRKSNVSA-N |
| Smiles | [H][C@]12OC3=C(C(=O)C=C4C(=O)C(C(=O)CCC)=C5C=C(C)OC3=C45)[C@@]1(O)[C@H](O)[C@H](OC)[C@@H](C)O2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light when in solution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antileishmanial agent. Active against Leishmania donovani, the causative agent of visceral leishmaniasis. Showed no activity against intracellular Leishmania.
- Amine-reactive fluorescent compound.
- Cytostatic.
- Weak cytotoxic (3-10 μM).
Product References
- Isolierung, Strukturaufklärung und Biosynthese der Isatropolone aus Streptomyces sp. Gö66: N. Pöhlmann; PhD Thesis; Univ. Göttingen, Cuvillier Verlag, Page 1-136 (2004) [ISBN 3-86537-286-4]
- Structure and biosynthesis of isatropolones, bioactive amine-scavenging fluorescent natural products from Streptomyces Gö66: X. Cai, et al.; Angew. Chem. Int. Ed. Engl. 56, 4945 (2017)
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