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BioViotica
Chrysomycin B
170
CHF
CHF 170.00
In stock
BVT-0100-C250250 µgCHF 170.00
BVT-0100-M0011 mgCHF 410.00
| Product Details | |
|---|---|
| Synonyms | Chrysomycin M; Virenomycin M |
| Product Type | Chemical |
| Properties | |
| Formula |
C27H28O9 |
| MW | 496.5 |
| CAS | 83852-56-6 |
| Source/Host Chemicals | Isolated from Streptomyces sp. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Yellow to greenish solid. |
| Solubility | Soluble in DMSO or dimethylformamide; slightly soluble in 100% ethanol or methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | BJPYMDSMDBCKEP-QSMCFSHASA-N |
| Smiles | COC1=CC2=C(OC(=O)C3=CC(C)=CC(OC)=C23)C2=C1C(O)=CC=C2[C@@H]1OC(C)[C@H](O)[C@](C)(O)C1O |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Topoisomerase II inhibitor.
- Mediates a unique cross-linking reaction between DNA and histidine H3.
- Anti-neoplastic.
- Photosensitizing compound.
- Antitumor compound against human cell lines.
- Less potent than chrysomycin A (Prod. No. BVT-0099).
Product References
- Chrysomycin: a new antibiotic substance for bacterial viruses: F. Strelitz, et al.; J. Bacteriol. 69, 280 (1955)
- The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A: U. Weiss, et al.; J. Antibiot. 35, 1194 (1982)
- Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II: A. Lorico and B.H. Long; Eur. J. Cancer 29A, 1985 (1993)
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