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BioViotica
Chrysomycin A
170
CHF
CHF 170.00
In stock
BVT-0099-C250250 µgCHF 170.00
BVT-0099-M0011 mgCHF 420.00
| Product Details | |
|---|---|
| Synonyms | Chrysomycin V; Virenomycin V |
| Product Type | Chemical |
| Properties | |
| Formula |
C28H28O9 |
| MW | 508.5 |
| CAS | 82196-88-1 |
| Source/Host Chemicals | Isolated from Streptomyces sp. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Yellow to greenish solid. |
| Solubility | Soluble in DMSO or dimethylformamide; slightly soluble in 100% ethanol or methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | OMDANBMKOUVKAG-WZNMFJNZSA-N |
| Smiles | COC1=CC2=C(OC(=O)C3=CC(C=C)=CC(OC)=C23)C2=C1C(O)=CC=C2[C@@H]1OC(C)[C@H](O)[C@](C)(O)C1O |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Topoisomerase II inhibitor.
- Mediates a unique cross-linking reaction between DNA and histidine H3.
- Anti-neoplastic.
- Photosensitizing compound.
- Antitumor compound against human cell lines.
Product References
- Chrysomycin: a new antibiotic substance for bacterial viruses: F. Strelitz, et al.; J. Bacteriol. 69, 280 (1955)
- The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A: U. Weiss, et al.; J. Antibiot. 35, 1194 (1982)
- Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II: A. Lorico & B.H. Long; Eur. J. Cancer 29A, 1985 (1993)
- Structures and biological activities of novel 4'-acetylated analogs of chrysomycins A and B: S. Wada, et al.; J. Antibiot. 70, 1078 (2017)
- Anti-microbial activity of chrysomycin A produced by Streptomyces sp. against Mycobacterium tuberculosis: B. Muralikrishnan, et al.; RSC Adv. 7, 36335 (2017)
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