BioViotica

Chrysomycin B

CHF 170.00
In stock
BVT-0100-C250250 µgCHF 170.00
BVT-0100-M0011 mgCHF 410.00
More Information
Product Details
Synonyms Chrysomycin M; Virenomycin M
Product Type Chemical
Properties
Formula

C27H28O9

MW 496.5
CAS 83852-56-6
Source/Host Chemicals Isolated from Streptomyces sp.
Purity Chemicals ≥98% (HPLC)
Appearance Yellow to greenish solid.
Solubility Soluble in DMSO or dimethylformamide; slightly soluble in 100% ethanol or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key BJPYMDSMDBCKEP-QSMCFSHASA-N
Smiles COC1=CC2=C(OC(=O)C3=CC(C)=CC(OC)=C23)C2=C1C(O)=CC=C2[C@@H]1OC(C)[C@H](O)[C@](C)(O)C1O
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Antibiotic.
  • Topoisomerase II inhibitor.
  • Mediates a unique cross-linking reaction between DNA and histidine H3.
  • Anti-neoplastic.
  • Photosensitizing compound.
  • Antitumor compound against human cell lines.
  • Less potent than chrysomycin A (Prod. No. BVT-0099).
Product References
  1. Chrysomycin: a new antibiotic substance for bacterial viruses: F. Strelitz, et al.; J. Bacteriol. 69, 280 (1955)
  2. The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A: U. Weiss, et al.; J. Antibiot. 35, 1194 (1982)
  3. Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II: A. Lorico and B.H. Long; Eur. J. Cancer 29A, 1985 (1993)
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