7-Methoxycoumarin-4-acetic acid

Specifications / Handling

More Information
Product Details
Synonyms	MCA; 7-MeO-Coumarin-AcOH; 7-Methoxy-2-oxo-2H-1-benzopyran-4-acetic acid; NSC 378137
Product Type	Chemical
Properties
Formula	C₁₂H₁₀O₅
MW	234.2
CAS	62935-72-2
Source/Host Chemicals	Synthetic
Purity Chemicals	≥97% (NMR)
Appearance	White powder.
Solubility	Soluble in DMF (50 mg/ml), acetone or DMSO.
Identity	Determined by NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	ZEKAXIFHLIITGV-UHFFFAOYSA-N
Smiles	COC1=CC=C2C(CC(O)=O)=CC(=O)OC2=C1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Florescent probe that is commonly used as a building block to synthesize coumarin-type fluorescent probes. Spectral data: λex 320 nm, λem 380 nm in methanol. It is used as a fluorescent label for peptides. It is widely used for developing FRET peptide substrates for analyzing protease activities and for HPLC derivatization by fluorescence detection.

Product References

(1) H. Mita, et al.; Anal. Biochem. 180, 131 (1989) | (2) C.G. Knight; Lett. Pept. Sci. 5, 1 (1998) | (3) C. Charitos, et al.; J. Pept. Res. 56, 373 (2000) | (4) G.A. Bannikov, et al.; J. Biol. Chem. 277, 16022 (2002) | (5) A. Ciencialova, et al.; J. Pept. Sci. 10, 470 (2004) | (6) L.E. Yandek, et al.; Biophys. J. 92, 2434 (2007) | (7) A. Lesner, et al.; Anal. Biochem. 375, 306 (2008)

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