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Chemodex
7-Methoxycoumarin-3-carboxylic acid
Product Details | |
---|---|
Synonyms | 7-Methoxy-2-oxo-2H-1-benzopyran-3-carboxylic acid |
Product Type | Chemical |
Properties | |
Formula |
C11H8O5 |
MW | 220.18 |
CAS | 20300-59-8 |
Source/Host Chemicals | Synthetic. |
Purity Chemicals | ≥97% (HPLC) |
Appearance | White to off-white solid. |
Solubility | Soluble in DMSO, DMF or acetonitrile. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | VEEGNDSSWAOLFN-UHFFFAOYSA-N |
Smiles | COC1=CC2=C(C=C1)C=C(C(O)=O)C(=O)O2 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
An amine-reactive blue fluorescent probe that provides a distinguishable contrast when used with longer-wavelength probes in certain multicolor fluorescence applications such as nucleic acid and protein microarrays, in situ hybridization and immunofluorescence. This carboxylic acid derivative of 7-methoxycoumarin can be used for coupling to amines, hydrazines or hydroxylamines on biomolecules of interest. Spectral data: Ex=336nm, Em=402nm (Buffer, pH9).
(1) T. Berthelot, et al.; J. Fluoresc. 14, 671 (2004) | (2) Y. Ma, et al.; J. Med. Chem. 47, 6349 (2004) | (3) M. Hagihara, et al.; JACS 128, 12932 (2006) | (4) H. Tetsuia, et al.; Pep. Sci. 43, 349 (2006) | (5) A.R. Katritzky, et al.; Synthesis 2011, 83 (2011) | (6) A.R. Katritzky, et al.; Synthesis 2011, 1494 (2011) | (7) L.T. Tegler, et al.; Angew. Chem. Int. Ed. 50, 1823 (2011)