7-Methoxycoumarin-4-acetic acid

CHF 122.00
In stock
CDX-M0028-M500500 mgCHF 122.00
CDX-M0028-G0011 gCHF 204.00
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Product Details
Synonyms MCA; 7-MeO-Coumarin-AcOH; 7-Methoxy-2-oxo-2H-1-benzopyran-4-acetic acid; NSC 378137
Product Type Chemical
Formula C12H10O5
MW 234.2
CAS 62935-72-2
Source/Host Chemicals Synthetic
Purity Chemicals ≥97% (NMR)
Appearance White powder.
Solubility Soluble in DMF (50 mg/ml), acetone or DMSO.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Smiles COC1=CC=C2C(CC(O)=O)=CC(=O)OC2=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Florescent probe that is commonly used as a building block to synthesize coumarin-type fluorescent probes. Spectral data: λex 320 nm, λem 380 nm in methanol. It is used as a fluorescent label for peptides. It is widely used for developing FRET peptide substrates for analyzing protease activities and for HPLC derivatization by fluorescence detection.

Product References

(1) H. Mita, et al.; Anal. Biochem. 180, 131 (1989) | (2) C.G. Knight; Lett. Pept. Sci. 5, 1 (1998) | (3) C. Charitos, et al.; J. Pept. Res. 56, 373 (2000) | (4) G.A. Bannikov, et al.; J. Biol. Chem. 277, 16022 (2002) | (5) A. Ciencialova, et al.; J. Pept. Sci. 10, 470 (2004) | (6) L.E. Yandek, et al.; Biophys. J. 92, 2434 (2007) | (7) A. Lesner, et al.; Anal. Biochem. 375, 306 (2008)

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