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BioViotica
Bacimethrin
155
CHF
CHF 155.00
In stock
BVT-0226-C500500 µgCHF 155.00
BVT-0226-M0011 mgCHF 275.00
| Product Details | |
|---|---|
| Synonyms | 4-Amino-2-methoxy-5-pyrimidinemethanol; 4-Amino-5-hydroxymethyl-2-methoxypyrimidine |
| Product Type | Chemical |
| Properties | |
| Formula |
C6H9N3O2 |
| MW | 155.2 |
| Merck Index | 12: 00964 |
| CAS | 3690-12-8 |
| Source/Host Chemicals | Isolated from Streptomyces albus. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Off-white powder. |
| Solubility | Soluble in DMSO (50mg/ml), methanol (15mg/ml) or water (10mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | ZPNHGSNYBLXGOL-UHFFFAOYSA-N |
| Smiles | COC1=NC(N)=C(CO)C=N1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Derivative of 5-Hydoxymethylcytosine (Prod. No. BVT-0229).
- Antibiotic.
- Antibacterial.
- Thiamine antagonist.
- Phosphatase kinase inhibitor.
Product References
- Biological studies on bacimethrin, a pyrimidine antibiotic, and monazomycin: T. Nishimura & N. Tanaka; J. Antibiot. 16, 179 (1963)
- Bacimethrin isolated from Streptomyces albus identification, derivatives, synthesis and biological properties: H. Drautz, et al.; J. Antibiot. 40, 1431 (1987)
- Nucleoside antibiotics: Structure, biological activity, and biosynthesis: K. Isono; J. Antibiot. 41, 1711 (1988) (Review)
- The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite: J.J. Reddick, et al.; Bioorg. Med. Chem. Lett. 11, 2245 (2001)
- Hydrophilic modifications in peptide nucleic acid - Synthesis and properties of PNA possessing 5-hydroxymethyluracil and 5-hydroxymethylcytosine: R.H.E. Hudson, et al.; Can. J. Chem. 85, 302 (2007)
- Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin: N.S Nemeria, et al.; Biochemistry 55, 1135 (2016)
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