BioViotica

β-Naphthocyclinone

CHF 145.00
In stock
BVT-0250-M0011 mgCHF 145.00
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Product Details
Product Type Chemical
Properties
Formula

C35H32O14

MW 676.6
CAS 55050-83-4
Source/Host Chemicals Isolated from Streptomyces arenae.
Purity Chemicals ≥98% (NMR, HPLC)
Appearance Red solid.
Solubility Soluble in DMSO, methanol, acetone or chloroform.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key ULOHVDHKDYSPRZ-YPPLNYSTSA-N
Smiles COC(=O)C[C@H]1CC2=CC3=C(C(=O)[C@H]4C[C@@]3(OC(C)=O)C3=C(O)C5=C(C(O)=C43)C(=O)C3=C(C[C@H](CC(O)=O)O[C@H]3C)C5=O)C(O)=C2[C@H](C)O1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Isochromane quinone antibiotic.
  • Antibacterial.
Product References
  1. Isolation and structure of the isochromanquinone antibiotics β- and γ-naphthocyclinone: A. Zeeck, et al.; Liebigs Ann. Chem. 1974, 1100 (1974)
  2. Biosynthetic relationships in the naphthocyclinone series of isochromane quinone antibiotics: B. Krone, et al.; J. Org. Chem. 47, 4721 (1982)
  3. New isochromanone antibiotics of the naphthocyclinone series: B. Krone & A. Zeeck; Liebigs Ann. Chem. 1983, 471 (1983)
  4. Isolation and characterization of the naphthocyclinone gene cluster from Streptomyces arenae DSM 40737 and heterologous expression of the polyketide synthase genes: P. Bruenker, et al.; Gene 227, 125 (1999)
  5. Heterologous expression of the naphthocyclinone hydroxylase gene from Streptomyces arenae for production of novel hybrid polyketides: P. Bruenker, et al.; Anton. Leeuw. Int. J. G. 79, 235 (2001)
  6. Molecular regulation of antibiotic biosynthesis in streptomyces: L. Gang, et al.; Microbiol. Mol. Biol. Rev. 77, 112 (2013)
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