Bacimethrin

CHF 160.00
In stock
BVT-0226-C500500 µgCHF 160.00
BVT-0226-M0011 mgCHF 275.00
More Information
Product Details
Synonyms 4-Amino-2-methoxy-5-pyrimidinemethanol; 4-Amino-5-hydroxymethyl-2-methoxypyrimidine
Product Type Chemical
Properties
Formula C6H9N3O2
MW 155.2
Merck Index 12: 00964
CAS 3690-12-8
Source/Host Chemicals Isolated from Streptomyces albus.
Purity Chemicals ≥98% (HPLC)
Appearance Off-white powder.
Solubility Soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key ZPNHGSNYBLXGOL-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Derivative of 5-Hydoxymethylcytosine (Prod. No. BVT-0229).
  • Antibiotic.
  • Antibacterial.
  • Thiamine antagonist.
  • Phosphatase kinase inhibitor.
Product References
  1. Biological studies on bacimethrin, a pyrimidine antibiotic, and monazomycin: T. Nishimura & N. Tanaka; J. Antibiot. 16, 179 (1963)
  2. Bacimethrin isolated from Streptomyces albus identification, derivatives, synthesis and biological properties: H. Drautz, et al.; J. Antibiot. 40, 1431 (1987)
  3. Nucleoside antibiotics: Structure, biological activity, and biosynthesis: K. Isono; J. Antibiot. 41, 1711 (1988) (Review)
  4. The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite: J.J. Reddick, et al.; Bioorg. Med. Chem. Lett. 11, 2245 (2001)
  5. Hydrophilic modifications in peptide nucleic acid - Synthesis and properties of PNA possessing 5-hydroxymethyluracil and 5-hydroxymethylcytosine: R.H.E. Hudson, et al.; Can. J. Chem. 85, 302 (2007)
  6. Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin: N.S Nemeria, et al.; Biochemistry 55, 1135 (2016)
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