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Chemodex
JC-1
312
CHF
CHF 312.00
In stock
CDX-T0046-M01010 mgCHF 312.00
CDX-T0046-M100100 mgCHF 1'628.00
| Product Details | |
|---|---|
| Synonyms | JC-1 jodide |
| Product Type | Chemical |
| Properties | |
| Formula | C25H27Cl4IN4 |
| MW | 652.23 |
| CAS | 3520-43-2 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥90% (HPLC) |
| Appearance | Dark violet solid. |
| Solubility | Soluble in methanol, DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | FYNNIUVBDKICAX-UHFFFAOYSA-M |
| Smiles | [I-].CCN1C(=C\C=C\C2=[N+](CC)C3=C(C=C(Cl)C(Cl)=C3)N2CC)N(CC)C2=C1C=C(Cl)C(Cl)=C2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.
Product References
(1) G.Y. Guralchuk et al.; J. Phys. Chem. C 112(38), 14762 (2008) | (2) S.T. Smiley et al.; PNAS 88, 3671 (1991) | (3) M. Reers, et al.; Biochem. 30, 4480 (1991)
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