Chemodex

3,3'-Dipropylthiacarbocyanine iodide

As low as CHF 39.00

In stock

Only %1 left

CDX-D0007-M05050 mgCHF 39.00

CDX-D0007-M250250 mgCHF 135.00

Specifications / Handling

More Information
Product Details
Synonyms	DiSC(3)(3)
Product Type	Chemical
Properties
Formula	C₂₃H₂₅IN₂S₂
MW	520.49
CAS	53336-12-2
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98% (NMR)
Appearance	Solid.
Solubility	Soluble in methanol, DMSO or DMF.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	JGTCEHAVVINOPG-UHFFFAOYSA-M
Smiles	[I-].CCCN1\C(SC2=C1C=CC=C2)=C/C=C/C1=[N+](CCC)C2=C(S1)C=CC=C2
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Carbocyanine dyes, particularly thiacyanines such as DiSC3(3) can inhibit respiration and may therefore be relatively cytotoxic. 3,3'-dipropyl-thiadicarbocyanine iodide is sensitive to membrane potential, fluorescence response to depolarization depends on the staining concentration and detection method.

Selected applications are:
-Calcium channels and other ion transport systems
-Mitochondrial activity
-Neurons and brain tissue
-Membrane potential in intact yeast cells

Product-specific References

(1) D. Gaskova et al.; Biochem. Biophys. Res. Comm. 354(3), 814 (2007) | (2) D. Gaskova et al.; Int. J. Biochem. Cell Biol., 34(8), 931 (2002) | (3) H. Amlal et al.; M. Bichara; J. Biol. Chem. 269, 21962 (1994) | (4) H.W. van Veen et al.; Biol. Chem. 269, 29509 (1994) | (5) L. Hunyady et al.; Am. J. Physiol. 266, C67 (1994)

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